Evidence map›Paper›PMID 32085432›Full record

ArticleMolecules (Basel, Switzerland)2020

Biophysical Characterization of Epigallocatechin-3-Gallate Effect on the Cardiac Sodium Channel Na

Mohamed-Yassine Amarouch, Han Kurt, Lucie Delemotte, Hugues Abriel

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.4field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 3 citations in OpenAlex.

  1. Review
  2. Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 3 countries.

Mohamed-Yassine AmarouchR.N.E Laboratory, Multidisciplinary Faculty of Taza, University Sidi Mohamed Ben Abdellah of Fez, Fez 30000, Morocco.
Han KurtScience for Life Laboratory, Department of Applied Physics, KTH Royal Institute of Technology, SE100 44 Solna, Sweden.
Lucie DelemotteScience for Life Laboratory, Department of Applied Physics, KTH Royal Institute of Technology, SE100 44 Solna, Sweden.
Hugues AbrielInstitute of Biochemistry and Molecular Medicine (IBMM), University of Bern, 3012 Bern, Switzerland.
Science for Life Laboratory · SESidi Mohamed Ben Abdellah University · MAUniversity of Bern · CH

Funding

The leading House from Middle East and North Africa, Switzerland grant number Seed Money 2018 - 09
6 · The paper itself

Abstract

Epigallocatechin-3-Gallate (EGCG) has been extensively studied for its protective effect against cardiovascular disorders. This effect has been attributed to its action on multiple molecular pathways and transmembrane proteins, including the cardiac Na

Indexed as

Biophysical PhenomenaCatechinCell LineCell Membrane PermeabilityHumansIon Channel GatingKineticsMolecular Dynamics SimulationMyocardiumNAV1.5 Voltage-Gated Sodium ChannelSodium Channel BlockersCatechinepigallocatechin gallateNAV1.5 Voltage-Gated Sodium ChannelSodium Channel Blockerscellular electrophysiologyEGCGion channelsmolecular dynamicsNav1.5

Identifiers

PMID32085432
PMCPMC7070937
OpenAlexW3008082568

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.