Evidence map›Paper›PMID 32085401›Full record

ArticleMaterials (Basel, Switzerland)2020

PEGylated Amine-Functionalized Poly(ε-caprolactone) for the Delivery of Plasmid DNA.

Amin Jafari, Nika Rajabian, Guojian Zhang, Mohamed Alaa Mohamed, Pedro Lei, Stelios T Andreadis, Blaine A Pfeifer, Chong Cheng

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Materials (Basel, Switzerland), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.6field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Article
  3. Well-Defined Diblock Poly(ethylene glycol)-Materials (Basel, Switzerland) · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 3 countries.

Amin JafariDepartment of Chemical and Biological Engineering, University at Buffalo, The State University of New York, Buffalo, NY 14260, USA.ORCID 0000-0002-0867-745X
Nika RajabianDepartment of Chemical and Biological Engineering, University at Buffalo, The State University of New York, Buffalo, NY 14260, USA.
Guojian ZhangDepartment of Chemical and Biological Engineering, University at Buffalo, The State University of New York, Buffalo, NY 14260, USA.ORCID 0000-0002-4976-8083
Mohamed Alaa MohamedDepartment of Chemical and Biological Engineering, University at Buffalo, The State University of New York, Buffalo, NY 14260, USA.
Pedro LeiDepartment of Chemical and Biological Engineering, University at Buffalo, The State University of New York, Buffalo, NY 14260, USA.
Stelios T AndreadisDepartment of Chemical and Biological Engineering, University at Buffalo, The State University of New York, Buffalo, NY 14260, USA.
Blaine A PfeiferDepartment of Chemical and Biological Engineering, University at Buffalo, The State University of New York, Buffalo, NY 14260, USA.ORCID 0000-0002-9338-2794
Chong ChengDepartment of Chemical and Biological Engineering, University at Buffalo, The State University of New York, Buffalo, NY 14260, USA.
University at Buffalo, State University of New York · USQingdao National Laboratory for Marine Science and Technology · CNMansoura University · EG

Funding

National Science Foundation DMR-1609914
6 · The paper itself

Abstract

As a promising strategy for the treatment of various diseases, gene therapy has attracted increasing attention over the past decade. Among various gene delivery approaches, non-viral vectors made of synthetic biomaterials have shown significant potential. Due to their synthetic nature, non-viral vectors can have tunable structures and properties by using various building units. In particular, they can offer advantages over viral vectors with respect to biosafety and cytotoxicity. In this study, a well-defined poly(ethylene glycol)-

Indexed as

cationic polymernanocomplexNon-viral gene deliveryPEGylationplasmid DNA (pDNA)poly(ethylene glycol)polyplexpoly(ε-caprolactone)ring-opening polymerization (ROP)

Identifiers

PMID32085401
PMCPMC7079624
OpenAlexW3008944290

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.