Evidence map›Paper›PMID 32085400›Full record

ArticleJournal of clinical medicine2020

Combining Novel Biomarkers for Risk Stratification of Two-Year Cardiovascular Mortality in Patients with ST-Elevation Myocardial Infarction.

Naufal Zagidullin, Lukas J Motloch, Diana Gareeva, Aysilu Hamitova, Irina Lakman, Ilja Krioni, Denis Popov, Rustem Zulkarneev, Vera Paar, Kristen Kopp and 5 more

Open access · goldAbstract read
In one paragraph

Article in Journal of clinical medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed, 4 pooled it
2.4field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 4 syntheses or guidelines pooled it, 46 citations in OpenAlex.

  1. Pooled it
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  5. Article
  6. Article
  7. Reperfusion injury in STEMI: a double-edged sword.The Egyptian heart journal : (EHJ) : official bulletin of the Egyptian Society of Cardiology · 2025
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  11. Impact of multiple substance use on circulating ST2, a biomarker of adverse cardiac remodelling, in women.Biomarkers : biochemical indicators of exposure, response, and susceptibility to chemicals · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 4 institutions in 2 countries.

Naufal ZagidullinDepartment of Internal Diseases, Bashkir State Medical University, Lenin str., 3, 450008 Ufa, Russia.ORCID 0000-0003-2386-6707
Lukas J MotlochUniversity Clinic for Internal Medicine II, Paracelsus Medical University, Muellner Hauptstrasse 48, 5020 Salzburg, Austria.
Diana GareevaDepartment of Internal Diseases, Bashkir State Medical University, Lenin str., 3, 450008 Ufa, Russia.
Aysilu HamitovaDepartment of Internal Diseases, Bashkir State Medical University, Lenin str., 3, 450008 Ufa, Russia.
Irina LakmanDepartment of Electronics and Biomedical Technology, Ufa State Aviation Technical University, Karl Marx str., 12, 450077 Ufa, Russia.ORCID 0000-0001-9876-9202
Ilja KrioniDepartment of Electronics and Biomedical Technology, Ufa State Aviation Technical University, Karl Marx str., 12, 450077 Ufa, Russia.
Denis PopovDepartment of Electronics and Biomedical Technology, Ufa State Aviation Technical University, Karl Marx str., 12, 450077 Ufa, Russia.
Rustem ZulkarneevDepartment of Internal Diseases, Bashkir State Medical University, Lenin str., 3, 450008 Ufa, Russia.
Vera PaarUniversity Clinic for Internal Medicine II, Paracelsus Medical University, Muellner Hauptstrasse 48, 5020 Salzburg, Austria.
Kristen KoppUniversity Clinic for Internal Medicine II, Paracelsus Medical University, Muellner Hauptstrasse 48, 5020 Salzburg, Austria.
Peter JirakUniversity Clinic for Internal Medicine II, Paracelsus Medical University, Muellner Hauptstrasse 48, 5020 Salzburg, Austria.
Vladimir IshmetovDepartment of Internal Diseases, Bashkir State Medical University, Lenin str., 3, 450008 Ufa, Russia.
Uta C HoppeUniversity Clinic for Internal Medicine II, Paracelsus Medical University, Muellner Hauptstrasse 48, 5020 Salzburg, Austria.
Eduard TulbaevDepartment of Internal Diseases, Bashkir State Medical University, Lenin str., 3, 450008 Ufa, Russia.
Valentin PavlovDepartment of Internal Diseases, Bashkir State Medical University, Lenin str., 3, 450008 Ufa, Russia.
Bashkir State Medical University · RUParacelsus Medical University · ATUfa State Aviation Technical University · RUBashkir State University · RU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

ST-elevation myocardial infarction (STEMI) is one of the main reasons for morbidity and mortality worldwide. In addition to the classic biomarker NT-proBNP, new biomarkers like ST2 and Pentraxin-3 (Ptx-3) have emerged as potential tools in stratifying risk in cardiac patients. Indeed, multimarker approaches to estimate prognosis of STEMI patients have been proposed and their potential clinical impact requires investigation. In our study, in 147 patients with STEMI, NT-proBNP as well as serum levels of ST2 and Ptx-3 were evaluated. During two-year follow-up (FU; 734.2 ± 61.2 d) results were correlated with risk for cardiovascular mortality (CV-mortality). NT-proBNP (HR = 1.64, 95% CI = 1.21-2.21,

Indexed as

cardiovascular deathcardiovascular eventsmyocardial infarctionNT-proBNPPentraxin-3risk stratificationsST2STEMI

Identifiers

PMID32085400
PMCPMC7073894
OpenAlexW3006812114

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.