Evidence map›Paper›PMID 32084556›Full record

ArticleMicrobes and infection2020

The Role of MicroRNA-155 in Chlamydia muridarum Infected lungs.

Jonathon Keck, James P Chambers, Aravind Kancharla, Dona Haj Bashir, Laura Henley, Katherine Schenkel, Kevin Castillo, M Neal Guentzel, Rishein Gupta, Bernard P Arulanandam

Open access · greenAbstract read
In one paragraph

Article in Microbes and infection, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.2field-weighted citation impact, top 49% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Influence of Fetuin-A onInternational journal of microbiology · 2022
    Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Jonathon KeckSouth Texas Center for Emerging Infectious Diseases, University of Texas at San Antonio, One UTSA Circle, San Antonio, TX, 78249, USA.
James P ChambersSouth Texas Center for Emerging Infectious Diseases, University of Texas at San Antonio, One UTSA Circle, San Antonio, TX, 78249, USA.
Aravind KancharlaSouth Texas Center for Emerging Infectious Diseases, University of Texas at San Antonio, One UTSA Circle, San Antonio, TX, 78249, USA.
Dona Haj BashirSouth Texas Center for Emerging Infectious Diseases, University of Texas at San Antonio, One UTSA Circle, San Antonio, TX, 78249, USA.
Laura HenleySouth Texas Center for Emerging Infectious Diseases, University of Texas at San Antonio, One UTSA Circle, San Antonio, TX, 78249, USA.
Katherine SchenkelSouth Texas Center for Emerging Infectious Diseases, University of Texas at San Antonio, One UTSA Circle, San Antonio, TX, 78249, USA.
Kevin CastilloSouth Texas Center for Emerging Infectious Diseases, University of Texas at San Antonio, One UTSA Circle, San Antonio, TX, 78249, USA.
M Neal GuentzelSouth Texas Center for Emerging Infectious Diseases, University of Texas at San Antonio, One UTSA Circle, San Antonio, TX, 78249, USA.
Rishein GuptaSouth Texas Center for Emerging Infectious Diseases, University of Texas at San Antonio, One UTSA Circle, San Antonio, TX, 78249, USA. Electronic address: Rishein.Gupta@utsa.edu.
Bernard P ArulanandamSouth Texas Center for Emerging Infectious Diseases, University of Texas at San Antonio, One UTSA Circle, San Antonio, TX, 78249, USA. Electronic address: Bernard.Arulanandam@utsa.edu.
Texas Center for Infectious Disease · US

Funding

The Contribution of MicroRNA-182 in Genital Chlamydia trachomatis InfectionR03AI117714 · NIAID · UNIVERSITY OF TEXAS SAN ANTONIO · PI ARULANANDAM, BERNARD PRAGASH · 2016 to 2017
$147k
NIAID NIH HHS R03 AI117714
6 · The paper itself

Abstract

Our laboratory has investigated the role of an evolutionarily conserved RNA species called microRNAs (miRs) in regulation of anti-chlamydial protective immunity. MiRs including miR-155 expressed in specific immune effector cells are critical for antigen specific protective immunity and IFN-γ production. Using miR-155 deficient mice, and a murine pulmonary model for chlamydial infection, we report here 1) the effect of host miR-155 on bacterial burden, and 2) identify probable immune genes regulated by miR-155.

Indexed as

AnimalsBacterial LoadChlamydia InfectionsChlamydia muridarumDisease Models, AnimalDisease ProgressionGene Expression RegulationInterferon-gammaLungMiceMicroRNAsInterferon-gammaMicroRNAsMirn155 microRNA, mouseBacterial burdensChlamydia spGene regulationIFN-γLungmicroRNAmiR-155

Identifiers

PMID32084556
PMCPMC7434643
OpenAlexW3008290577

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.