Evidence map›Paper›PMID 32084445›Full record

ArticleProgress in cardiovascular diseases

Reducing cardiovascular risk among people living with HIV: Rationale and design of the INcreasing Statin Prescribing in HIV Behavioral Economics REsearch (INSPIRE) randomized controlled trial.

Sae Takada, Allison J Ober, Judith S Currier, Noah J Goldstein, Tamara B Horwich, Brian S Mittman, Suzanne B Shu, Chi-Hong Tseng, Tara Vijayan, Soma Wali and 2 more

Open access · greenAbstract readClinical Trial Protocol
PubMed Full text at PMC Publisher
In one paragraph

Article in Progress in cardiovascular diseases. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.5field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 10 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 5 institutions in 1 country.

Sae TakadaDivision of General Internal Medicine and Health Services Research, Department of Medicine, Geffen School of Medicine at University of California, Los Angeles (UCLA), Los Angeles, CA, USA.
Allison J OberRAND Corporation, Santa Monica, CA, USA.
Judith S CurrierDivision of Infectious Diseases, Department of Medicine, Geffen School of Medicine at UCLA, Los Angeles, CA, USA.
Noah J GoldsteinUCLA Anderson School of Management, Los Angeles, CA, USA; Department of Psychology, UCLA, Los Angeles, CA, USA.
Tamara B HorwichDivision of Cardiology, Department of Medicine, Geffen School of Medicine at UCLA, Los Angeles, CA, USA.
Brian S MittmanDivision of Health Services Research & Implementation Science, Department of Research & Evaluation, Kaiser Permanente Southern California, Pasadena, CA, USA.
Suzanne B ShuUCLA Anderson School of Management, Los Angeles, CA, USA.
Chi-Hong TsengDivision of General Internal Medicine and Health Services Research, Department of Medicine, Geffen School of Medicine at University of California, Los Angeles (UCLA), Los Angeles, CA, USA.
Tara VijayanDivision of Infectious Diseases, Department of Medicine, Geffen School of Medicine at UCLA, Los Angeles, CA, USA.
Soma WaliDepartment of Medicine, Olive View-UCLA Medical Center, Sylmar, CA, USA.
William E CunninghamDivision of General Internal Medicine and Health Services Research, Department of Medicine, Geffen School of Medicine at University of California, Los Angeles (UCLA), Los Angeles, CA, USA.
Joseph A LadapoDivision of General Internal Medicine and Health Services Research, Department of Medicine, Geffen School of Medicine at University of California, Los Angeles (UCLA), Los Angeles, CA, USA. Electronic address: JLadapo@mednet.ucla.edu.
University of California, Los Angeles · USAnderson University - South Carolina · USKaiser Permanente · USOlive View-UCLA Medical Center · USRAND Corporation · US

Funding

Behavioral Economics and Implementation Research to Reduce Cardiovascular Risk in HIV-infected AdultsU01HL142104 · NHLBI · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI DIAMANT, ALLISON LESLIE · 2018 to 2021
$2.7M
AHRQ HHS K12 HS026407NHLBI NIH HHS U01 HL142104
6 · The paper itself

Abstract

Cardiovascular disease (CVD) is a major cause of morbidity among people living with HIV (PLWH). Statins can safely and effectively reduce CVD risk in PLWH, but evidence-based statin therapy is under-prescribed in PLWH. Developed using an implementation science framework, INcreasing Statin Prescribing in HIV Behavioral Economics REsearch (INSPIRE) is a stepped-wedge cluster randomized trial that addresses organization-, clinician- and patient-level barriers to statin uptake in Los Angeles community health clinics serving racially and ethnically diverse PLWH. After assessing knowledge about statins and barriers to clinician prescribing and patient uptake, we will design, implement and measure the effectiveness of (1) educational interventions targeting leadership, clinicians, and patients, followed by (2) behavioral economics-informed clinician feedback on statin uptake. In addition, we will assess implementation outcomes, including changes in clinician acceptability of statin prescribing for PLWH, clinician acceptability of the education and feedback interventions, and cost of implementation.

Indexed as

Attitude of Health PersonnelEconomics, BehavioralPractice Patterns, Physicians'Preventive Health ServicesAnti-HIV AgentsCardiovascular DiseasesDrug PrescriptionsEducation, Medical, ContinuingHealth Knowledge, Attitudes, PracticeHealth StatusHIV InfectionsHIV Long-Term SurvivorsHumansHydroxymethylglutaryl-CoA Reductase InhibitorsImplementation ScienceInservice TrainingAnti-HIV AgentsHydroxymethylglutaryl-CoA Reductase InhibitorsBehavioral economicsCardiovascular diseaseHIVImplementation scienceStatins

Identifiers

PMID32084445
PMCPMC8670826
OpenAlexW3006800501

What OpenQuestion holds

Texttitle and abstract
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.