Evidence map›Paper›PMID 32084052›Full record

ArticleJournal of acquired immune deficiency syndromes (1999)2020

Toward Universal HIV Treatment in Haiti: Time Trends in ART Retention After Expanded ART Eligibility in a National Cohort From 2011 to 2017.

Nancy Puttkammer, Canada Parrish, Yrvel Desir, Nathaelf Hyppolite, Bradley H Wagenaar, Nadjy Joseph, Lara Hall, Jean Guy Honoré, Ermane Robin, Georges Perrin and 1 more

Open access · greenAbstract read
In one paragraph

Article in Journal of acquired immune deficiency syndromes (1999), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
0.3field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 17 citations in OpenAlex.

  1. Trends and Disruptions in Antiretroviral Treatment Enrollment in Haiti, 2018-2024.The American journal of tropical medicine and hygiene · 2026
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  5. Treatment Outcomes After Offering Same-Day Initiation of Human Immunodeficiency Virus Treatment-How to Interpret Discrepancies Between Different Studies.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 5 institutions in 2 countries.

Nancy PuttkammerDepartments of Global Health; and.
Canada ParrishHealth Services Research, International Training and Education Center for Health (I-TECH), University of Washington, Seattle, WA.
Yrvel DesirNational Association of State and Territorial AIDS Directors (NASTAD), Port-au-Prince, Haiti.
Nathaelf HyppoliteFormerly with Centre Haitien de Renforcement du Système Sanitaire (CHARESS), Port-au-Prince, Haiti.
Bradley H WagenaarDepartment of Global Health, University of Washington, Seattle, WA.
Nadjy JosephNational Association of State and Territorial AIDS Directors (NASTAD), Port-au-Prince, Haiti.
Lara HallDivision of Global HIV & Tuberculosis, US Centers for Disease Control and Prevention, Port-au-Prince, Haiti.
Jean Guy HonoréCentre Haitien de Renforcement du Système Sanitaire (CHARESS), Port-au-Prince, Haiti; and.
Ermane RobinProgramme National de Lutte contre le VIH/SIDA (PNLS), Ministère de Santé Publique et de la Population (MSSP), Port-au-Prince, Haiti.
Georges PerrinDivision of Global HIV & Tuberculosis, US Centers for Disease Control and Prevention, Port-au-Prince, Haiti.
Kesner FrançoisProgramme National de Lutte contre le VIH/SIDA (PNLS), Ministère de Santé Publique et de la Population (MSSP), Port-au-Prince, Haiti.
Gheskio Centers · HTNational Alliance of State and Territorial AIDS Directors · USCenter for Global Health · USHealth Services Research & Development · USUniversity of Washington · US

Funding

University of Washington/Fred Hutch Center for AIDS ResearchP30AI027757 · NIAID · UNIVERSITY OF WASHINGTON · PI EDWIN ROBERTO ORELLANA · 1988 to 2026
$104.9M
CGH CDC HHS U2G GH001130NIAID NIH HHS P30 AI027757PEPFAR
6 · The paper itself

Abstract

backgroundThe World Health Organization (WHO) recommends universal antiretroviral therapy (ART) for persons living with HIV (PLWH), but evidence about effects of expanded ART access on ART retention in low-resource settings is limited.

settingHaiti's Ministry of Health endorsed universal ART for pregnant women in March 2013 (Option B+) and for all PLWH in July 2016. This study included 51,579 ART patients from 2011 to 2017 at 94 hospitals and clinics in Haiti.

methodsThis observational, retrospective cohort study described time trends in 6-month ART retention using secondary data, and compared results during 3 periods using an interrupted time series model: pre-Option B+ (period 1: 1/11-2/13), Option B+ (period 2: 3/13-6/16), and Test and Start (T&S, period 3: 7/16-9/17).

resultsFrom the pre-Option B+ to the T&S period, the monthly count of new ART patients increased from 366/month to 877/month, and the proportion with same-day ART increased from 6.3% to 42.1% (P < 0.001). The proportion retained on ART after 6 months declined from 78.4% to 75.0% (P < 0.001). In the interrupted time series model, ART retention improved by a rate of 1.4% per quarter during the T&S period after adjusting for patient characteristics (adjusted incidence rate ratio = 1.014; 95% confidence interval: 1.002 to 1.026, P < 0.001). However, patients with same-day ART were 14% less likely to be retained compared to those starting ART >30 days after HIV diagnosis (adjusted incidence rate ratio = 0.86; 95% confidence interval: 0.84-0.89, P < 0.001).

conclusionsAchieving targets for HIV epidemic control will require increasing ART retention and reducing the disparity in retention for those with same-day ART.

Indexed as

HIV-1AdultAnti-HIV AgentsCohort StudiesFemaleHaitiHIV InfectionsHumansMaleRetrospective StudiesAnti-HIV Agents

Identifiers

PMID32084052
PMCPMC7228851
OpenAlexW3008253091

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.