ArticleOrthopaedic journal of sports medicine2020
An Analysis of Current Treatment Trends in Platelet-Rich Plasma Therapy in the Medicare Database.
Article in Orthopaedic journal of sports medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
22 citing papers in PubMed, 1 synthesis or guideline pooled it, 37 citations in OpenAlex.
- Does intra-articular injection of PRP help patients with temporomandibular joint osteoarthritis after joint puncture? a systematic review and meta-analysis of randomized controlled trials.BMC oral health · 2025Pooled it
- Trial
- Evolving Treatment Options for Spinal Pain: Balancing Innovation and Affordability in Regenerative Medicine.Current pain and headache reports · 2026Review
- Health Disparities in Orthobiologics: Factors Influencing Access to Platelet-Rich Plasma for Knee Osteoarthritis.Orthopaedic journal of sports medicine · 2026Article
- The Availability and Pricing of Orthobiologic Knee Injections in the Chicago Metropolitan Area: A Market Assessment Study.Orthopaedic journal of sports medicine · 2025Article
- Efficacy of intra-articular injections for the treatment of osteoarthritis: A narrative review.Osteoarthritis and cartilage open · 2025Article
- The Current Status and Future Prospects of Intra-articular Injection Therapy for Hip Osteoarthritis: A Review.Current pain and headache reports · 2025Review
- Platelet-rich plasma improves pain and function in knee osteoarthritis: a retrospective study.Frontiers in physiology · 2025Article
- Randomized Controlled Trials for Platelet-Rich Plasma Use in Knee Osteoarthritis Rarely Report Key Sociodemographic Patient Variables: A Scoping Review.Arthroscopy, sports medicine, and rehabilitation · 2024Article
- Platelet-rich plasma intra-articular knee injections from open preparation techniques do not pose a higher risk of joint infection: A systematic review of 91 randomized controlled trials and 5914 injections.Journal of experimental orthopaedics · 2024Review
- Time to Total Knee Arthroplasty (TKA) Post Intra-Articular Injection.Journal of clinical medicine · 2024Article
- Allogeneic platelet-rich plasma for knee osteoarthritis in patients with primary immune thrombocytopenia: A randomized clinical trial.iScience · 2024Article
- Article
- Platelet-Rich Plasma Versus Corticosteroid Injections for the Treatment of Mild-to-Moderate Carpal Tunnel Syndrome: A Markov Cost-Effectiveness Decision Analysis.Hand (New York, N.Y.) · 2024Article
- A Comprehensive Review on Platelet-Rich Plasma Activation: A Key Player in Accelerating Skin Wound Healing.Cureus · 2023Review
- Public Interest in Shoulder Platelet-Rich Plasma Injections Is Increasing: A 10-Year Google Trends Analysis.Arthroscopy, sports medicine, and rehabilitation · 2023Article
- Effect of Bone Marrow Aspirate Concentrate and Platelet-Rich Plasma Augmentation on the Rate of Revision Rotator Cuff Repair.Orthopaedic journal of sports medicine · 2022Article
- Patients seeking stem cell therapies-a prospective qualitative analysis from a Regenerative Medicine Consult Service.NPJ Regenerative medicine · 2022Article
- Transforaminal Endoscopic Lumbar Discectomy with versus without Platelet-Rich Plasma Injection for Lumbar Disc Herniation: A Prospective Cohort Study.Pain research & management · 2022Article
- Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe use of platelet-rich plasma (PRP) in the Medicare population is not well described. PURPOSE: To investigate the national use of PRP among Medicare beneficiaries, including the incidence and conditions for which it was used in both operative and nonoperative settings, and determine charges to Medicare. STUDY
designDescriptive epidemiology study.
methodsThe Medicare Standard Analytical Files within the PearlDiver database were queried for PRP injections by use of Current Procedural Terminology (CPT) code 0232T from 2010 to 2014. A search of every associated International Classification of Diseases, 9th Revision, code and CPT code on the day of the injection was performed, and codes were broadly categorized as shoulder, knee, elbow, hip, and foot/ankle. These categories were then subdivided into 2 groups based on whether the injection was performed at the time of surgery or for a nonoperative condition. The patient data were analyzed by demographics and geographic region. In further analysis, the charges sent to Medicare for PRP injections were stratified by year and musculoskeletal site.
resultsA total of 3654 PRP injections were coded for and administered during the study period; 57% of recipients were men and 33% were 65 to 69 years of age. We found that 42% of all PRP injections were administered in the southern geographic region. PRP injections were most commonly associated with shoulder diagnoses, followed closely by the foot and ankle and by the knee. The majority of injections given for shoulder conditions were performed at the time of surgery, whereas the majority of knee conditions treated with PRP were associated with nonoperative treatments. Annual charges to Medicare for PRP injections increased 400%, from $500,000 in 2010 to more than $2 million in 2014.
conclusionThe use and breadth of PRP therapy have increased substantially in Medicare beneficiaries. Further research is required to obtain a consensus on treatment recommendations for PRP use in this population in addition to strategies to obtain insurance reimbursement.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.