Evidence map›Paper›PMID 32083052›Full record

ReviewFrontiers in chemistry2020

Self-Assemblable Polymer Smart-Blocks for Temperature-Induced Injectable Hydrogel in Biomedical Applications.

Thai Thanh Hoang Thi, Le Hoang Sinh, Dai Phu Huynh, Dai Hai Nguyen, Cong Huynh

Abstract readReview
In one paragraph

Review in Frontiers in chemistry, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed.

  1. Review
  2. Article
  3. [Application and progress of intelligent responsive hydrogels in articular cartilage injury repair].Zhongguo xiu fu chong jian wai ke za zhi = Zhongguo xiufu chongjian waike zazhi = Chinese journal of reparative and reconstructive surgery · 2025
    Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. In Situ Hydrogels for Effective Treatment of Cancer: Strategies and Polymers Used.Recent advances in drug delivery and formulation · 2022
    Article
  10. Article
  11. Review
  12. Self-Assembling Hydrogel Structures for Neural Tissue Repair.ACS biomaterials science & engineering · 2021
    Review
  13. Supramolecular Gels IncorporatingInternational journal of molecular sciences · 2021
    Article
  14. Review
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Thai Thanh Hoang ThiBiomaterials and Nanotechnology Research Group, Faculty of Applied Sciences, Ton Duc Thang University, Ho Chi Minh City, Vietnam.
Le Hoang SinhInstitute of Research and Development, Duy Tan University, Da Nang, Vietnam.
Dai Phu HuynhFaculty of Materials Technology and Polymer Research Center, Ho Chi Minh City University of Technology, VNU HCM, Ho Chi Minh City, Vietnam.
Dai Hai NguyenInstitute of Applied Materials Science, Vietnam Academy of Science and Technology, Ho Chi Minh City, Vietnam.
Cong HuynhInstitute of Research and Development, Duy Tan University, Da Nang, Vietnam.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Self-assembled temperature-induced injectable hydrogels fabricated via self-assembly of polymer smart-blocks have been widely investigated as drug delivery systems and platforms for tissue regeneration. Polymer smart-blocks that can be self-assembly play an important role in fabrication of hydrogels because they can self-assemble to induce the gelation of their copolymer in aqueous solution. The self-assembly occurs in response to an external stimulus change, such as temperature, pH, glucose, ionic strength, light, magnetic field, electric field, or their combination, which results in property transformations like hydrophobicity, ionization, and conformational change. The self-assembly smart-block based copolymers exist as a solution in aqueous media at certain conditions that are suitable for mixing with bioactive molecules and/or cells. However, this solution turns into a hydrogel due to the self-assembly of the smart-blocks under exposure to an external stimulus change

Indexed as

biomaterialsblock copolymerdrug delivery systemhydrogelsinjectableself-assemblytemperature-sensitivetissue engineering

Identifiers

PMID32083052
PMCPMC7005785

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.