Evidence map›Paper›PMID 32083024›Full record

ArticleFrontiers in cellular and infection microbiology2019

Structural and Functional Characterization of the Gut Microbiota in Elderly Women With Migraine.

Juanjuan Chen, Qi Wang, Anqi Wang, Zhanglin Lin

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in cellular and infection microbiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 55 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
55citing papers in PubMed, 4 pooled it
5.1field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

55 citing papers in PubMed, 4 syntheses or guidelines pooled it, 92 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Pooled it
  5. Review
  6. ProbioticBrain sciences · 2026
    Article
  7. Review
  8. Article
  9. Article
  10. Review
  11. Article
  12. Review
  13. Review
  14. Article
  15. Review
  16. Article
  17. Review
  18. Article
  19. The Gut Microbiome and Migraine: Updates in Understanding.Current neurology and neuroscience reports · 2025
    Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 1 country.

Juanjuan ChenSchool of Biology and Biological Engineering, South China University of Technology, Guangzhou, China.
Qi WangBGI-Shenzhen, Shenzhen, China.
Anqi WangLanzhou University, Lanzhou, China.
Zhanglin LinSchool of Biology and Biological Engineering, South China University of Technology, Guangzhou, China.
South China University of Technology · CNLanzhou University · CNUniversity of Chinese Academy of Sciences · CN

Funding

Department of HealthWellcome TrustWellcome Trust 105022/Z/14/Z
6 · The paper itself

Abstract

Migraine is a very common, multifactorial, and recurrent central nervous system disorder that causes throbbing headache, photophobia, phonophobia, nausea, and disability. Migraine occurs more often in females, and its complex physiopathology is not yet fully understood. An increasing number of gastrointestinal disorders have been linked to the occurrence of migraine suggesting that gut microbiota might play a pivotal role in migraine through the gut-brain axis. In the present work, we performed a metagenome-wide association study (MWAS) to determine the relationship between gut microbiota and migraine by analyzing 108 shotgun-sequenced fecal samples obtained from elderly women who suffer from migraine and matched healthy controls. Notably, the alpha diversity was significantly decreased in the migraine group at species, genus, and Kyoto Encyclopedia of Genes and Genomes (KEGG) orthologous levels. Firmicutes, especially the "unfriendly"

Indexed as

AdenosineAgedBacteriaBifidobacterium adolescentisFaecalibacterium prausnitziiFecesFemaleGastrointestinal MicrobiomeGastrointestinal TractHumansMetagenomeMethanobrevibacterMigraine DisordersPrognosisQuinolinic AcidSpermidineAdenosineadenosylspermidineQuinolinic AcidSpermidineelderly womenfunctional modulesgut microbiotametagenome-wide association studymigrainestructural characterization

Identifiers

PMID32083024
PMCPMC7001586
OpenAlexW3004327143

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.