Evidence map›Paper›PMID 32082254›Full record

ArticleFrontiers in endocrinology2019

Exposure to the UV Filter Octyl Methoxy Cinnamate in the Postnatal Period Induces Thyroid Dysregulation and Perturbs the Immune System of Mice.

Fausto Klabund Ferraris, Esdras Barbosa Garcia, Amanda da Silva Chaves, Thais Morais de Brito, Laís Higino Doro, Naína Monsores Félix da Silva, Amanda Soares Alves, Tatiana Almeida Pádua, Maria das Graças M O Henriques, Tiago Savignon Cardoso Machado and 1 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in endocrinology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.3field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 20 citations in OpenAlex.

  1. Article
  2. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 1 institution in 1 country.

Fausto Klabund FerrarisLaboratory of Pharmacology, Department of Pharmacology and Toxicology, National Institute of Health Quality Control (INCQS)-Oswaldo Cruz Foundation (FIOCRUZ), Rio de Janeiro, Brazil.
Esdras Barbosa GarciaLaboratory of Pharmacology, Department of Pharmacology and Toxicology, National Institute of Health Quality Control (INCQS)-Oswaldo Cruz Foundation (FIOCRUZ), Rio de Janeiro, Brazil.
Amanda da Silva ChavesLaboratory of Pharmacology, Department of Pharmacology and Toxicology, National Institute of Health Quality Control (INCQS)-Oswaldo Cruz Foundation (FIOCRUZ), Rio de Janeiro, Brazil.
Thais Morais de BritoLaboratory of Pharmacology, Department of Pharmacology and Toxicology, National Institute of Health Quality Control (INCQS)-Oswaldo Cruz Foundation (FIOCRUZ), Rio de Janeiro, Brazil.
Laís Higino DoroLaboratory of Pharmacology, Department of Pharmacology and Toxicology, National Institute of Health Quality Control (INCQS)-Oswaldo Cruz Foundation (FIOCRUZ), Rio de Janeiro, Brazil.
Naína Monsores Félix da SilvaLaboratory of Pharmacology, Department of Pharmacology and Toxicology, National Institute of Health Quality Control (INCQS)-Oswaldo Cruz Foundation (FIOCRUZ), Rio de Janeiro, Brazil.
Amanda Soares AlvesLaboratory of Pharmacology, Department of Pharmacology and Toxicology, National Institute of Health Quality Control (INCQS)-Oswaldo Cruz Foundation (FIOCRUZ), Rio de Janeiro, Brazil.
Tatiana Almeida PáduaLaboratory of Applied Pharmacology, Institute of Drug Technology (Far-Manguinhos)-Oswaldo Cruz Foundation (FIOCRUZ), Rio de Janeiro, Brazil.
Maria das Graças M O HenriquesLaboratory of Applied Pharmacology, Institute of Drug Technology (Far-Manguinhos)-Oswaldo Cruz Foundation (FIOCRUZ), Rio de Janeiro, Brazil.
Tiago Savignon Cardoso MachadoLaboratory of Professional Education in Laboratory Techniques in Health, Polytechnic School of Health Joaquim Venâncio-Oswaldo Cruz Foundation (FIOCRUZ), Rio de Janeiro, Brazil.
Fabio Coelho AmendoeiraLaboratory of Pharmacology, Department of Pharmacology and Toxicology, National Institute of Health Quality Control (INCQS)-Oswaldo Cruz Foundation (FIOCRUZ), Rio de Janeiro, Brazil.
Fundação Oswaldo Cruz · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Evidence demonstrates the bidirectional communication and regulation between the neuroendocrine and immune systems. Thyroid hormones play key roles in nervous system development and can exert influence on various immune cells contributing to pathophysiological conditions. Octyl methoxycinnamate (OMC) is one of the most commonly used UV filters, and

Indexed as

hypothyroidismimmune systemoctyl methoxycinnamateOMCsunscreenthyroid disruptorUV filter

Identifiers

PMID32082254
PMCPMC7005579
OpenAlexW3003255397

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.