Evidence map›Paper›PMID 32082240›Full record

ArticleFrontiers in neurology2020

Persistent Feeding and Swallowing Deficits in a Mouse Model of 22q11.2 Deletion Syndrome.

Lauren Welby, Hailey Caudill, Gelila Yitsege, Ali Hamad, Filiz Bunyak, Irene E Zohn, Thomas Maynard, Anthony-Samuel LaMantia, David Mendelowitz, Teresa E Lever

Open access · goldAbstract read
In one paragraph

Article in Frontiers in neurology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 1 pooled it
1.8field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 1 synthesis or guideline pooled it, 27 citations in OpenAlex.

  1. A Systematic Review of Oropharyngeal Dysphagia Models in Rodents.International journal of environmental research and public health · 2021
    Pooled it
  2. Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Review
  16. Review
  17. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 5 institutions in 1 country.

Lauren WelbyDepartment of Otolaryngology Head and Neck Surgery, School of Medicine, University of Missouri, Columbia, MO, United States.
Hailey CaudillDepartment of Pharmacology and Physiology, School of Medicine and Health Sciences, The George Washington University, Washington, DC, United States.
Gelila YitsegeCenter for Genetic Medicine and the Center for Neuroscience Research, Children's National Medical Center, Children's National Health Systems, Washington, DC, United States.
Ali HamadDepartment of Electrical Engineering and Computer Science, University of Missouri, Columbia, MO, United States.
Filiz BunyakDepartment of Electrical Engineering and Computer Science, University of Missouri, Columbia, MO, United States.
Irene E ZohnDepartment of Pharmacology and Physiology, School of Medicine and Health Sciences, The George Washington University, Washington, DC, United States.
Thomas MaynardLaboratory of Developmental Disorders and Genetics, Virginia Tech-Carilion School of Medicine, The Fralin Biomedical Research Institute, Roanoke, VA, United States.
Anthony-Samuel LaMantiaLaboratory of Developmental Disorders and Genetics, Virginia Tech-Carilion School of Medicine, The Fralin Biomedical Research Institute, Roanoke, VA, United States.
David MendelowitzDepartment of Pharmacology and Physiology, School of Medicine and Health Sciences, The George Washington University, Washington, DC, United States.
Teresa E LeverDepartment of Otolaryngology Head and Neck Surgery, School of Medicine, University of Missouri, Columbia, MO, United States.
University of Missouri · USChildren's National · USGeorge Washington University · USBiomedical Research Institute · USVirginia Tech · US

Funding

Pathology, Developmental Origins, and Prevention of Pediatric DysphagiaP01HD083157 · NICHD · GEORGE WASHINGTON UNIVERSITY · PI LAMANTIA, ANTHONY S · 2015 to 2019
$6.4M
Research_ProjectU54HD090257 · NICHD · CHILDREN'S RESEARCH INSTITUTE · PI VITTORIO GALLO, VITTORIO GALLO VITTORIO GALLO · 2016 to 2020
$5.9M
NICHD NIH HHS P01 HD083157NICHD NIH HHS U54 HD090257
6 · The paper itself

Abstract

Disrupted development of oropharyngeal structures as well as cranial nerve and brainstem circuits may lead to feeding and swallowing difficulties in children with 22q11. 2 deletion syndrome (22q11DS). We previously demonstrated aspiration-based dysphagia during early postnatal life in the

Indexed as

22q11 deletion syndromedeglutitionDiGeorge syndromedysphagiafeedingmouse modelpediatric dysphagia

Identifiers

PMID32082240
PMCPMC7006055
OpenAlexW3004316998

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.