Evidence map›Paper›PMID 32082108›Full record

ArticleFrontiers in neuroscience2020

Altered Amplitude of Low-Frequency Fluctuations and Functional Connectivity in Excessive Daytime Sleepiness in Parkinson Disease.

Xixi Wang, Min Wang, Yongsheng Yuan, Junyi Li, Yuting Shen, Kezhong Zhang

Open access · goldAbstract read
In one paragraph

Article in Frontiers in neuroscience, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 1 pooled it
1.2field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 1 synthesis or guideline pooled it, 13 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Xixi WangDepartment of Neurology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China.
Min WangDepartment of Radiology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China.
Yongsheng YuanDepartment of Neurology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China.
Junyi LiDepartment of Neurology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China.
Yuting ShenDepartment of Neurology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China.
Kezhong ZhangDepartment of Neurology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China.
Jiangsu Province Hospital · CNNanjing Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectExcessive daytime sleepiness (EDS) is common in Parkinson disease (PD), but the neural basis of EDS in PD is unclear. We aim to analyze the neural activity changes in PD-related EDS.

methodsIn the present study, 38 PD patients and 19 healthy controls underwent clinical assessments and resting state functional magnetic resonance imaging (MRI) at 3T. Patients were further classified into PD patients with EDS (

resultsWe found that, all PD-EDS subjects in our study were male. Compared with the control subjects, PD patients with EDS had decreased ALFF in the Pons and increased ALFF in the Frontal_Mid_Orb_L (

conclusionWe hypothesized the wake-promoting pathways and the default mode network dysfunction underlying the EDS in male PD patients.

Indexed as

amplitude of low-frequency fluctuationsexcessive daytime sleepinessfunctional connectivityParkinson diseaseresting-state functional MRI

Identifiers

PMID32082108
PMCPMC7006219
OpenAlexW3004037391

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.