Evidence map›Paper›PMID 32082048›Full record

ArticleInfectious diseases2020

Outcome of Critically Ill Patients With Influenza Infection: A Retrospective Study.

Timothée Abaziou, Clément Delmas, Fanny Vardon Bounes, Fabien Bignon, Laure Crognier, Thierry Seguin, Béatrice Riu-Poulenc, Stéphanie Ruiz, Antoine Rouget, Pierre Cougot and 3 more

Abstract read
In one paragraph

Article in Infectious diseases, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Timothée AbaziouDepartment of Anesthesiology and Intensive Care, University Hospital of Toulouse, Toulouse, France.ORCID https://orcid.org/0000-0003-0493-3441
Clément DelmasIntensive Cardiac Care Unit, Rangueil University Hospital, Toulouse, France.ORCID https://orcid.org/0000-0001-9180-9128
Fanny Vardon BounesDepartment of Anesthesiology and Intensive Care, University Hospital of Toulouse, Toulouse, France.
Fabien BignonDepartment of Anesthesiology, Joseph Ducuing Hospital, Toulouse, France.
Laure CrognierDepartment of Anesthesiology and Intensive Care, University Hospital of Toulouse, Toulouse, France.
Thierry SeguinDepartment of Anesthesiology and Intensive Care, University Hospital of Toulouse, Toulouse, France.
Béatrice Riu-PoulencDepartment of Anesthesiology and Intensive Care, University Hospital of Toulouse, Toulouse, France.
Stéphanie RuizDepartment of Anesthesiology and Intensive Care, University Hospital of Toulouse, Toulouse, France.
Antoine RougetDepartment of Anesthesiology and Intensive Care, University Hospital of Toulouse, Toulouse, France.
Pierre CougotDepartment of Anesthesiology and Intensive Care, University Hospital of Toulouse, Toulouse, France.
Bernard GeorgesDepartment of Anesthesiology and Intensive Care, University Hospital of Toulouse, Toulouse, France.
Jean-Marie ConilDepartment of Anesthesiology and Intensive Care, University Hospital of Toulouse, Toulouse, France.
Vincent MinvilleDepartment of Anesthesiology and Intensive Care, University Hospital of Toulouse, Toulouse, France.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundInfluenza causes significant morbidity and mortality in adults, and numerous patients require intensive care unit (ICU) admission. Acute respiratory distress syndrome (ARDS) is clearly described in this context, but other clinical presentations exist that need to be assessed for incidence and outcome. The primary goal of this study was to describe the characteristics of patients admitted in ICU for influenza, their clinical presentation, and the 3-month mortality rate. The second objective was to search for 3-month mortality risk factors.

methodsThis is a retrospective study including all patients admitted to 3 ICUs due to influenza-related disease between October 2013 and June 2016, which assesses the 3-month mortality rate. We compared clinical presentation, biological data, and outcome at 3 months between survivors and non-survivors. We created a predicting 3-month mortality model with Classification and Regression Tree analysis.

resultsSixty-nine patients were included, 50 patients (72.5%) for ARDS, 5 (7.2%) for myocarditis, and 14 (20.3%) for acute respiratory failure without ARDS criteria. Non-typed influenza A was found in 30 cases (43.5%), influenza A H1N1 in 18 (26.1%), H3N2 in 3 (4.3%), and influenza B in 18 cases (27.5%). The 3-month mortality rate was 29% (

conclusionInfluenza in ICUs may have several clinical presentations. The mortality rate is high, but ECMO may be an effective rescue therapy.

Indexed as

acute respiratory failureARDSECMOICUInfluenzamyocarditis

Identifiers

PMID32082048
PMCPMC7005979

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.