ArticleScientific reports2020
Kynurenine Pathway as a New Target of Cognitive Impairment Induced by Lead Toxicity During the Lactation.
Open access · goldAbstract read
In one paragraph
Article in Scientific reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
1.2field-weighted citation impact, top 26% of its field
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
23 citing papers in PubMed, 28 citations in OpenAlex.
- Significance of NAD anabolism profiles in neurological diseases.Metabolic brain disease · 2026Review
- Cross-link Between CircRNAs and Neuroinflammation in Parkinson's Disease.Molecular neurobiology · 2026Review
- Sulfur-Containing Amino Acid Homeostasis in the Central Nervous System: From Physiology Regulation to Metal-Induced Neurotoxicity.Metabolites · 2026Review
- Endocrine-disrupting properties of heavy metal exposure contribute to the intergenerational effects on learning and memory.Frontiers in endocrinology · 2026Review
- Tryptophan Metabolism in Neurodevelopment and Its Implications For Neurodevelopmental Disorders.Molecular neurobiology · 2025Review
- Article
- Microplastics Accumulation Induces Kynurenine-Derived Neurotoxicity in Cerebral Organoids and Mouse Brain.Biomolecules & therapeutics · 2025Article
- Association Study Between Kynurenine 3-Monooxygenase (KMO) Gene and Parkinson's Disease Patients.Molecular neurobiology · 2024Article
- To explore the protective effect of gastrodin on PC12 cells against oxidative stress induced by lead acetate based on network pharmacology.Toxicology research · 2024Article
- Neuropathogenesis-on-chips for neurodegenerative diseases.Nature communications · 2024Review
- Early-Life Lead Exposure: Risks and Neurotoxic Consequences.Current medicinal chemistry · 2024Review
- Modulation of Kynurenic Acid Production by N-acetylcysteine Prevents Cognitive Impairment in Adulthood Induced by Lead Exposure during Lactation in Mice.Antioxidants (Basel, Switzerland) · 2023Article
- Kynurenine, Kynurenic Acid, Quinolinic Acid and Interleukin-6 Levels in the Serum of Patients with Autism Spectrum Disorder.Medicina (Kaunas, Lithuania) · 2023Article
- Bioinformatic Analysis of Kynurenine Pathway Enzymes and Their Relationship with Glioma Hallmarks.Metabolites · 2022Article
- Kynurenine and oxidative stress in children having learning disorder with and without attention deficit hyperactivity disorder: possible role and involvement.BMC neurology · 2022Article
- Role of Environmental Toxicants on Neurodegenerative Disorders.Frontiers in toxicology · 2022Review
- Kynurenine Pathway Metabolites as Biomarkers in Alzheimer's Disease.Disease markers · 2022Review
- Kynurenic acid in neurodegenerative disorders-unique neuroprotection or double-edged sword?CNS neuroscience & therapeutics · 2022Review
- Article
- Evaluation of Analytes Characterized with Potential Protective Action after Rat Exposure to Lead.Molecules (Basel, Switzerland) · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
14 authors at 3 institutions in 1 country.
Daniela Ramirez OrtegaLaboratorio de Neurobioquímica y Conducta, Departamento de Neuroquímica, Instituto Nacional de Neurología y Neurocirugía Manuel Velasco Suárez, S.S.A., México D.F, 14269, México.
Paulina Ovalle RodríguezLaboratorio de Neurobioquímica y Conducta, Departamento de Neuroquímica, Instituto Nacional de Neurología y Neurocirugía Manuel Velasco Suárez, S.S.A., México D.F, 14269, México.
Benjamín PinedaLaboratorio de Neuroinmunología, Instituto Nacional de Neurología y Neurocirugía Manuel Velasco Suárez, S.S.A., México D.F, 14269, México.
Dinora F González EsquivelLaboratorio de Neurobioquímica y Conducta, Departamento de Neuroquímica, Instituto Nacional de Neurología y Neurocirugía Manuel Velasco Suárez, S.S.A., México D.F, 14269, México.
Lucio Antonio Ramos ChávezLaboratorio de Neurobioquímica y Conducta, Departamento de Neuroquímica, Instituto Nacional de Neurología y Neurocirugía Manuel Velasco Suárez, S.S.A., México D.F, 14269, México.ORCID http://orcid.org/0000-0002-9701-3398
Gustavo I Vázquez CervantesLaboratorio de Neurobioquímica y Conducta, Departamento de Neuroquímica, Instituto Nacional de Neurología y Neurocirugía Manuel Velasco Suárez, S.S.A., México D.F, 14269, México.
Gabriel Roldán RoldánLaboratorio de Neurobiología de la Conducta, Departamento de Fisiología, Facultad de Medicina, Universidad Nacional Autónoma de México, Ciudad de México, 04510, México.
Gonzalo Pérez de la CruzFacultad de Ciencias, Departamento de Matemáticas, UNAM. Circuito Exterior, CU, 04510, Ciudad de México, México.
Araceli Díaz RuizLaboratorio de Neurobioquímica y Conducta, Departamento de Neuroquímica, Instituto Nacional de Neurología y Neurocirugía Manuel Velasco Suárez, S.S.A., México D.F, 14269, México.
Marisela Méndez ArmentaLaboratorio de Neuropatología Experimental, Instituto Nacional de Neurología y Neurocirugía, Manuel Velasco Suárez, S.S.A., México D.F, 14269, México.
Jaime Marcial QuinoCONACYT- Instituto Nacional de Pediatría, Secretaría de Salud, Ciudad de México, 04530, México.
Saul Gómez ManzoLaboratorio de Bioquímica Genética, Instituto Nacional de Pediatría, Secretaría de Salud, México City, 04530, México.
Camilo RíosLaboratorio de Neurobioquímica y Conducta, Departamento de Neuroquímica, Instituto Nacional de Neurología y Neurocirugía Manuel Velasco Suárez, S.S.A., México D.F, 14269, México.
Verónica Pérez de la CruzLaboratorio de Neurobioquímica y Conducta, Departamento de Neuroquímica, Instituto Nacional de Neurología y Neurocirugía Manuel Velasco Suárez, S.S.A., México D.F, 14269, México. veped@yahoo.com.mx.
Instituto Nacional de Neurología y Neurocirugía · MXInstituto Nacional de Pediatria · MXUniversidad Nacional Autónoma de México · MX
Funding
No grant is acknowledged in the PubMed record.
Abstract
The immature brain is especially vulnerable to lead (Pb
Indexed as
LactationAnimalsBrainCognitive DysfunctionEnvironmental ExposureFemaleKynurenineLeadMemory DisordersMemory, Long-TermMiceMotor ActivityOxidation-ReductionKynurenineLead
Identifiers
What OpenQuestion holds
Textmetadata
LicenceCC BY
Read underepoch 390
Registered trials
None linked
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.