SynthesisNPJ primary care respiratory medicine2020
Daytime symptoms of chronic obstructive pulmonary disease: a systematic review.
Synthesis in NPJ primary care respiratory medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
20 citing papers in PubMed, 1 synthesis or guideline pooled it, 31 citations in OpenAlex.
- The impact of long-acting muscarinic antagonists on mucus hypersecretion and cough in chronic obstructive pulmonary disease: a systematic review.European respiratory review : an official journal of the European Respiratory Society · 2022Pooled it
- Screening for Neurocognitive Abilities Post-COVID (SNAP-COVID): Scale Development and Validation.Medicina (Kaunas, Lithuania) · 2026Article
- Article
- Integrative multi-omics and machine learning identify CHRNA1 putative circadian-immune hub in COPD.PloS one · 2026Article
- Patient Participation in Monitoring Potential Adverse Drug Events.Applied clinical informatics · 2025Observational
- Review
- From data to medical context: the power of categorization in healthcare.Frontiers in medicine · 2025Article
- Chronobiology in breathlessness across 24 h in people with persistent breathlessness.ERJ open research · 2025Article
- The Humanistic and Economic Burden of COPD Patients in Urban China: A Propensity Score Matching Study.International journal of chronic obstructive pulmonary disease · 2025Article
- Measuring burden of disease in both asthma and COPD by merging the ACQ and CCQ: less is more?NPJ primary care respiratory medicine · 2024Article
- The six-minute step test can predict COPD exacerbations: a 36-month follow-up study.Scientific reports · 2024Article
- The effects of camel milk in systemic inflammation and oxidative stress of cigarette smoke-induced chronic obstructive pulmonary disease model in rat.Frontiers in veterinary science · 2024Article
- The Experiences of Individuals with a History of Acute Exacerbations of COPD and Their Thoughts on Death: Empirical Qualitative Research.Chronic obstructive pulmonary diseases (Miami, Fla.) · 2023Article
- Evaluation of the Norwegian version of the Dyspnoea-12 questionnaire in patients with COPD.BMJ open respiratory research · 2022Article
- Participatory methods in a digital setting: experiences from the co-creation of an eHealth tool for people with chronic obstructive pulmonary disease.BMC medical informatics and decision making · 2022Article
- Relationship between Peak Inspiratory Flow and Patient and Disease Characteristics in Individuals with COPD-A Systematic Scoping Review.Biomedicines · 2022Article
- The Relationship between Experienced Respiratory Symptoms and Health-Related Quality of Life in the Elderly with Chronic Obstructive Pulmonary Disease.Critical care research and practice · 2021Article
- Gender Differences in Chronic Obstructive Pulmonary Disease Symptom Clusters.International journal of chronic obstructive pulmonary disease · 2021Article
- How to Assess Breathlessness in Chronic Obstructive Pulmonary Disease.International journal of chronic obstructive pulmonary disease · 2021Review
- Adapting a digital monitoring system for self-management to geriatric COPD rehabilitation: A participatory mixed method study.Digital healthArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 2 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
There is no single source of compiled data on symptoms experienced by patients with chronic obstructive pulmonary disease (COPD) when awake and active throughout the day. The aim of this systematic review was to evaluate the prevalence, variability, and burden (i.e., bothersomeness and/or intensity), and the impact of daytime COPD symptoms on other outcomes. The review also evaluated the impact of interventions and the measures/tools used to assess daytime COPD symptoms in patients. A systematic literature search was conducted using the primary search terms "COPD", "symptoms", and "daytime" in EMBASE®, MEDLINE®, MEDLINE® In-Process, and CENTRAL in 2016, followed by an additional search in 2018 to capture any new literature that was published since the last search. Fifty-six articles were included in the review. The accumulated evidence indicated that the symptomatic burden of COPD appears greatest in the morning, particularly upon waking, and that these morning symptoms have a substantial impact on patients' ability to function normally through the day; they also worsen quality of life. A wide variety of tools were used to evaluate symptoms across the studies. The literature also confirmed the importance of pharmacotherapy in the management of daytime COPD symptoms, and in helping normalize daily functioning. More research is needed to better understand how COPD symptoms impact daily functioning and to evaluate COPD symptoms at well-defined periods throughout the day, using validated and uniform measures/tools. This will help clinicians to better define patients' needs and take appropriate action.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.