Evidence map›Paper›PMID 32081883›Full record

ArticleScientific reports2020

Resting State Functional Connectivity of the Thalamus in North Korean Refugees with and without Posttraumatic Stress Disorder.

Sehyun Jeon, Yu Jin Lee, Inkyung Park, Nambeom Kim, Soohyun Kim, Jin Yong Jun, So Young Yoo, So Hee Lee, Seog Ju Kim

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
2.3field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 27 citations in OpenAlex.

  1. Article
  2. Functional brain imaging in posttraumatic stress disorder: a review.Journal of neural transmission (Vienna, Austria : 1996) · 2026
    Review
  3. Decoding Transdiagnostic Subtypes in Emotional Disorders.CNS neuroscience & therapeutics · 2026
    Article
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  7. Mechanistic signatures of comorbid PTSD with cognitive impairment implicate cortisol-induced neural toxicity.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2026
    Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Review
  14. Biological Psychiatry in Displaced Populations: What We Know, and What We Need to Begin to Learn.Biological psychiatry. Cognitive neuroscience and neuroimaging · 2022
    Review
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. The Role of the Thalamus in Post-Traumatic Stress Disorder.International journal of molecular sciences · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 1 country.

Sehyun JeonDepartment of Psychiatry, Sungkyunkwan University School of Medicine, Samsung Medical Center, Seoul, Republic of Korea.
Yu Jin LeeDepartment of Psychiatry and Center for Sleep and Chronobiology, Seoul National University College of Medicine and Seoul National University Hospital, Seoul, Republic of Korea.
Inkyung ParkDepartment of Psychiatry and Center for Sleep and Chronobiology, Seoul National University College of Medicine and Seoul National University Hospital, Seoul, Republic of Korea.
Nambeom KimDepartment of Biomedical Engineering Research Center, Gachon University, Incheon, Republic of Korea.
Soohyun KimDepartment of Neurology, Gangneung Asan Hospital, Gangwon-do, Republic of Korea.
Jin Yong JunNational Center for Mental Health, Seoul, Republic of Korea.
So Young YooDepartment of Psychiatry, National Medical Center, Seoul, Republic of Korea.
So Hee LeeDepartment of Psychiatry, National Medical Center, Seoul, Republic of Korea.
Seog Ju KimDepartment of Psychiatry, Sungkyunkwan University School of Medicine, Samsung Medical Center, Seoul, Republic of Korea. ksj7126@skku.edu.ORCID http://orcid.org/0000-0003-2467-5451
Samsung Medical Center · KRNational Medical Center · KRSeoul National University Hospital · KRGachon University · KR

Funding

Mechanisms of Health and Disease at the Behavioral-Biomedical InterfaceT32GM108540 · NIGMS · UNIVERSITY OF IOWA · PI LUTGENDORF, SUSAN K, VOSS, MICHELLE WEBB · 2014 to 2023
$1.7M
NIGMS NIH HHS T32 GM108540
6 · The paper itself

Abstract

In posttraumatic stress disorder (PTSD), functional connectivity (FC) between the thalamus and other brain areas has yet to be comprehensively investigated. The present study explored resting state FC (rsFC) of thalamus and its associations with trauma-related features. The included subjects were North Korean refugees with PTSD (n = 23), trauma-exposed North Korean refugees without PTSD (trauma-exposed control [TEC] group, n = 22), and South Korean healthy controls (HCs) without traumatic experiences (HC group, n = 40). All participants underwent psychiatric evaluation and functional magnetic resonance imaging (fMRI) procedures using the bilateral thalamus as seeds. In the TEC group, the negative rsFC between each thalamus and its contralateral postcentral cortex was stronger relative to the PTSD and HC groups, while positive rsFC between the left thalamus and left precentral cortex was stronger in the HC group compared to the PTSD and TEC groups. Thalamo-postcentral rsFC was positively correlated with the CAPS total score in the TEC group, and with the number of traumatic experiences in the PTSD group. The present study identified the difference of thalamic rsFC alterations among traumatized refugees and HCs. Negative rsFC between the thalamus and somatosensory cortices might be compensatory changes after multiple traumatic events in refugees.

Indexed as

RefugeesAdultBrain MappingCase-Control StudiesDemocratic People's Republic of KoreaFemaleHumansMagnetic Resonance ImagingMaleReproducibility of ResultsRepublic of KoreaResilience, PsychologicalStress Disorders, Post-TraumaticStress, PsychologicalThalamus

Identifiers

PMID32081883
PMCPMC7035375
OpenAlexW3007317281

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.