Observational studyScientific reports2020
Age of puberty and Sleep duration: Observational and Mendelian randomization study.
Observational study in Scientific reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
14 citing papers in PubMed, 1 synthesis or guideline pooled it, 24 citations in OpenAlex.
- Methodological approaches, challenges, and opportunities in the application of Mendelian randomisation to lifecourse epidemiology: A systematic literature review.European journal of epidemiology · 2024Pooled it
- The association between age at menarche and subsequent risk of chronic pain.Frontiers in global women's health · 2026Review
- Trajectory and Trend of Weight Status, Emotional Wellbeing and Sleep From Infancy to Childhood to Adolescence in Scotland: An Analysis of Growing up in Scotland Birth Cohort 1.Pediatric obesity · 2025Article
- Shorter weeknight sleep duration mediates the relationship between earlier adrenarche and depressed mood in adolescents.Journal of affective disorders · 2025Article
- Examining Health Behaviors as Mechanisms Linking Earlier Pubertal Timing with Accelerated Epigenetic Aging in Late Adolescence.Journal of youth and adolescence · 2025Article
- Article
- Influence of the typology and timing of childhood trauma in psychoticism.Archives of women's mental health · 2024Article
- Mechanism of leptin-NPY on the onset of puberty in male offspring rats after androgen intervention during pregnancy.Frontiers in endocrinology · 2023Article
- Puberty signs and its relationship with lifestyle in 8-to-10-year-old girls: A descriptive-analytical study.Journal of family medicine and primary care · 2022Article
- Age, Period, and Cohort Effects of Internalizing Symptoms Among US Students and the Influence of Self-Reported Frequency of Attaining 7 or More Hours of Sleep: Results From the Monitoring the Future Survey 1991-2019.American journal of epidemiology · 2022Article
- Traumatic Brain Injury Characteristics Predictive of Subsequent Sleep-Wake Disturbances in Pediatric Patients.Biology · 2022Article
- The onset of pubertal development and actigraphy-assessed sleep during middle childhood: Racial, gender, and genetic effects.Sleep health · 2022Article
- Impact of sleep patterns upon female neuroendocrinology and reproductive outcomes: a comprehensive review.Reproductive biology and endocrinology : RB&E · 2022Review
- Association of body composition with pubertal timing in children and adolescents from Guangzhou, China.Frontiers in public health · 2022Article
Corrections and comments
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Authors and funding
8 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Earlier age of puberty has detrimental consequences for many aspects of health. Here, for the first time, we assessed the association of earlier puberty with sleep duration observationally and with validation using Mendelian Randomization. In the "Children of 1997" birth cohort (n = 8,327), we used adjusted multivariable logistic regression to assess the associations of each clinically assessed marker of earlier puberty with self-report sleep duration in adolescence. Using two-sample MR, we assessed the effect of earlier puberty timing based on 203 single nucleotide polymorphisms applied to genome wide association studies of sleep duration in adults (n = 335,410). In "Children of 1997", cross-sectionally, older age of menarche was associated with longer (9+ hours) sleep duration [odds ratio (OR) 1.11, 95% confidence interval (CI) 1.01 to 1.21] at 13.5 years. The other earlier puberty markers were unrelated to sleep duration. Using inverse variance weighting, later of age at menarche increased adult sleep duration [0.020 per category, 95% CI 0.006 to 0.034]. This study demonstrated a causal effect of age at menarche on adult sleep duration, since age of menarche also affects obesity, our novel finding may be relevant to the observed relation of sleep duration with obesity and poor health.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.