ArticleThe American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry2020
Dimensions of Poststroke Depression and Neuropsychological Deficits in Older Adults.
Article in The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.
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Who cites it
12 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Motivation as a Measurable Outcome in Stroke Rehabilitation: A Systematic Review of the Literature.International journal of environmental research and public health · 2023Pooled it
- Active Rehabilitation Technologies for Post-Stroke Patients.Biosensors · 2025Review
- The Dominance of Attentional Focus in Sitting Postural Control Among Patients with Stroke and the Characteristics of the Disconnectome.Journal of clinical medicine · 2025Article
- Depressive Symptoms Profiles and Cognitive Outcomes After Stroke.Brain and behavior · 2025Article
- The effect of motivational interviewing on patients with early post-stroke depression: a quasi-experimental study.BMC psychiatry · 2025Article
- Infarct volume as a predictor and therapeutic target in post-stroke cognitive impairment.Frontiers in medicine · 2025Review
- Factor structure and reliability of the symptom measurement of post-stroke depression in the rehabilitation stage.BMC psychiatry · 2024Article
- Neuroimaging of neuropsychological disturbances following ischaemic stroke (CONNECT): a prospective cohort study protocol.BMJ open · 2024Article
- A Review on Motor Imagery with Transcranial Alternating Current Stimulation: Bridging Motor and Cognitive Welfare for Patient Rehabilitation.Brain sciences · 2023Review
- Rest-Activity Rhythm Characteristics Associated With Depression Symptoms in Stroke Survivors.Archives of physical medicine and rehabilitation · 2023Observational
- The Impact of Post-Stroke Depressive Symptoms on Cognitive Performance in Women and in Men: A 4 Month Prospective Study.Life (Basel, Switzerland) · 2023Article
- Exploring the Use of Brain-Computer Interfaces in Stroke Neurorehabilitation.BioMed research international · 2021Review
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Authors and funding
8 authors.
Funding
Abstract
objectivePoststroke depression (PSD) has a heterogeneous presentation and is often accompanied by cognitive impairment. This study aimed to identify distinct dimensions of depressive symptoms in older adults with PSD and to evaluate their relationship to cognitive functioning.
designCross-sectional factor and correlational analyses of patients with poststroke depression.
settingPatients were recruited from the community and from acute inpatient stroke rehabilitation hospitals.
participantsParticipants had suffered a stroke and met DSM-IV criteria for major depression (≥18 Montgomery Åsberg Depression Scale; MADRS).
interventionNone. MEASUREMENTS: MADRS was used to quantify depression severity at study entry. Neuropsychological assessment at the time of study entry consisted of measures of Global Cognition, Attention, Executive Function, Processing Speed, Immediate Memory, Delayed Memory, and Language.
resultsThere were 135 (age ≥50) older adult participants with PSD and varying degrees of cognitive impairment (MMSE Total ≥20). Factor analysis of the MADRS identified three factors, that is sadness, distress, and apathy. Items comprising each factor were totaled and correlated with neuropsychological domain z-score averages. Symptoms of the apathy factor (lassitude, inability to feel) were significantly associated with greater impairment in executive function, memory, and global cognition. Symptoms of the sadness and distress factors had no relationship to cognitive impairment.
conclusionPSD consists of three correlated dimensions of depressive symptoms. Apathy symptoms are associated with cognitive impairment across several neuropsychological domains. PSD patients with prominent apathy may benefit from careful attention to cognitive functions and by interventions that address both psychopathology and behavioral deficits resulting from cognitive impairment.
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