Evidence map›Paper›PMID 32081008›Full record

ArticleJournal of medicinal chemistry2020

Synthesis and Characterization of Fluorine-18-Labeled

Junfeng Wang, Xiying Qu, Timothy M Shoup, Gengyang Yuan, Sepideh Afshar, Chuzhi Pan, Aijun Zhu, Ji-Kyung Choi, Hye Jin Kang, Pekka Poutiainen and 3 more

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of medicinal chemistry, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.5field-weighted citation impact, top 43% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 9 citations in OpenAlex.

  1. Highlights on U.S. FDA-approved halogen-containing drugs in 2024.European journal of medicinal chemistry · 2025
    Review
  2. Article
  3. Review
  4. Unexpected Intermolecular C-H···O Hydrogen Bonds andThe journal of physical chemistry. B · 2024
    Article
  5. Recent Advances of S-ACS omega · 2023
    Review
  6. Article
  7. Detailed radiosynthesis of [Journal of labelled compounds & radiopharmaceuticals · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 3 institutions in 3 countries.

Junfeng WangGordon Center for Medical Imaging, Massachusetts General Hospital and Harvard Medical School, 125 Nashua Street, Suite 660, Boston, Massachusetts 02114, United States.
Xiying QuGordon Center for Medical Imaging, Massachusetts General Hospital and Harvard Medical School, 125 Nashua Street, Suite 660, Boston, Massachusetts 02114, United States.
Timothy M ShoupGordon Center for Medical Imaging, Massachusetts General Hospital and Harvard Medical School, 125 Nashua Street, Suite 660, Boston, Massachusetts 02114, United States.
Gengyang YuanGordon Center for Medical Imaging, Massachusetts General Hospital and Harvard Medical School, 125 Nashua Street, Suite 660, Boston, Massachusetts 02114, United States.
Sepideh AfsharGordon Center for Medical Imaging, Massachusetts General Hospital and Harvard Medical School, 125 Nashua Street, Suite 660, Boston, Massachusetts 02114, United States.
Chuzhi PanGordon Center for Medical Imaging, Massachusetts General Hospital and Harvard Medical School, 125 Nashua Street, Suite 660, Boston, Massachusetts 02114, United States.
Aijun ZhuGordon Center for Medical Imaging, Massachusetts General Hospital and Harvard Medical School, 125 Nashua Street, Suite 660, Boston, Massachusetts 02114, United States.
Ji-Kyung ChoiAthinoula A. Martinos Center for Biomedical Imaging, Massachusetts General Hospital and Harvard Medical School, 149 Thirteenth Street, Suite 2301, Charlestown, Massachusetts 02129, United States.
Hye Jin KangDepartment of Pharmacology, University of North Carolina Chapel Hill School of Medicine, Chapel Hill, North Carolina 27514, United States.
Pekka PoutiainenUniversity Central Hospital of Kuopio, 70210 Kuopio, Finland.
Georges El FakhriGordon Center for Medical Imaging, Massachusetts General Hospital and Harvard Medical School, 125 Nashua Street, Suite 660, Boston, Massachusetts 02114, United States.
Zhaoda ZhangAthinoula A. Martinos Center for Biomedical Imaging, Massachusetts General Hospital and Harvard Medical School, 149 Thirteenth Street, Suite 2301, Charlestown, Massachusetts 02129, United States.
Anna-Liisa BrownellGordon Center for Medical Imaging, Massachusetts General Hospital and Harvard Medical School, 125 Nashua Street, Suite 660, Boston, Massachusetts 02114, United States.ORCID 0000-0002-3814-868X
Harvard University · USKuopio University Hospital · FIUniversity of North Carolina at Chapel Hill · US

Funding

ROLE OF DIETARY CONSTITUENTS ON GENE EXPRESSION IN INTESTINAL EPITHELIUMP30DK040561 · NIDDK · MASSACHUSETTS GENERAL HOSPITAL · PI Elizabeth Austen Lawson, Takara Leah Stanley · 1994 to 2026
$31.6M
Unified Joint Statistical Reconstruction of PET & MRP41EB022544 · NIBIB · YALE UNIVERSITY · PI Georges El Fakhri · 2017 to 2026
$14.8M
Positive Allosteric Modulators as PET Imaging Ligans for mGluR4R01NS100164 · NINDS · MASSACHUSETTS GENERAL HOSPITAL · PI BROWNELL, ANNA-LIISA, ZHANG, ZHAODA · 2016 to 2020
$3.7M
Designing group specific PET ligands for mGluR2R01EB021708 · NIBIB · MASSACHUSETTS GENERAL HOSPITAL · PI BROWNELL, ANNA-LIISA, ZHANG, ZHAODA · 2016 to 2019
$2.2M
Positive allosteric modulators as PET imaging ligands for mGluR4R01EB012864 · NIBIB · MASSACHUSETTS GENERAL HOSPITAL · PI BROWNELL, ANNA-LIISA · 2011 to 2014
$2.2M
Electronics Upgrade for 11.7 TS10OD025234 · OD · MASSACHUSETTS GENERAL HOSPITAL · PI CARAVAN, PETER D · 2018 to 2018
$595k
F-18 SynthesizerS10RR023452 · NCRR · MASSACHUSETTS GENERAL HOSPITAL · PI BROWNELL, ANNA-LIISA · 2007 to 2007
$500k
NCRR NIH HHS S10 RR023452NIBIB NIH HHS P41 EB022544NIBIB NIH HHS R01 EB012864NIBIB NIH HHS R01 EB021708NIDDK NIH HHS P30 DK040561NIH HHS S10 OD025234NIMH NIH HHS HHSN271201300017CNINDS NIH HHS R01 NS100164
6 · The paper itself

Abstract

We have synthesized and characterized [

Indexed as

AnimalsBrainDrug StabilityFluorine RadioisotopesLigandsMaleMicrosomes, LiverPicolinesPositron-Emission TomographyRadiopharmaceuticalsRats, Sprague-DawleyReceptors, Metabotropic GlutamateFluorine-18Fluorine RadioisotopesLigandsmetabotropic glutamate receptor 4PicolinesRadiopharmaceuticalsReceptors, Metabotropic Glutamate

Identifiers

PMID32081008
PMCPMC7261135
OpenAlexW3008281638

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.