Evidence map›Paper›PMID 32080990›Full record

ArticleJournal of Korean medical science2020

Virus Isolation from the First Patient with SARS-CoV-2 in Korea.

Wan Beom Park, Nak Jung Kwon, Su Jin Choi, Chang Kyung Kang, Pyoeng Gyun Choe, Jin Yong Kim, Jiyoung Yun, Gir Won Lee, Moon Woo Seong, Nam Joong Kim and 2 more

Open access · goldAbstract readCase Reports
In one paragraph

Article in Journal of Korean medical science, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 124 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
124citing papers in PubMed, 1 pooled it
5.7field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

124 citing papers in PubMed, 1 synthesis or guideline pooled it, 241 citations in OpenAlex.

  1. Pooled it
  2. Observational
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  11. Autophagy in Inflammatory Response against SARS-CoV-2.International journal of molecular sciences · 2023
    Review
  12. Article
  13. Article
  14. Gastrointestinal symptoms in COVID-19.Przeglad gastroenterologiczny · 2023
    Review
  15. Article
  16. Review
  17. Article
  18. Article
  19. Review
  20. Article

64 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 5 institutions in 1 country.

Wan Beom Park *Department of Internal Medicine, Seoul National University College of Medicine, Seoul, Korea.ORCID https://orcid.org/0000-0003-0022-9625
Nak Jung Kwon *Macrogen Inc., Seoul, Korea.ORCID https://orcid.org/0000-0003-0874-4146
Su Jin ChoiLaboratory of Infection & Immunity, Seoul National University Hospital Biomedical Research Institute, Seoul, Korea.ORCID https://orcid.org/0000-0001-8732-3950
Chang Kyung KangDepartment of Internal Medicine, Seoul National University College of Medicine, Seoul, Korea.ORCID https://orcid.org/0000-0003-1952-072X
Pyoeng Gyun ChoeDepartment of Internal Medicine, Seoul National University College of Medicine, Seoul, Korea.ORCID https://orcid.org/0000-0001-6794-7918
Jin Yong KimDepartment of Internal Medicine, Incheon Medical Center, Incheon, Korea.ORCID https://orcid.org/0000-0002-4306-1597
Jiyoung YunMacrogen Inc., Seoul, Korea.ORCID https://orcid.org/0000-0002-5752-7423
Gir Won LeeMacrogen Inc., Seoul, Korea.ORCID https://orcid.org/0000-0002-1621-1713
Moon Woo SeongDepartment of Laboratory Medicine, Seoul National University College of Medicine, Seoul, Korea.ORCID https://orcid.org/0000-0003-2954-3677
Nam Joong KimDepartment of Internal Medicine, Seoul National University College of Medicine, Seoul, Korea.ORCID https://orcid.org/0000-0001-6793-9467
Jeong Sun SeoMacrogen Inc., Seoul, Korea.ORCID https://orcid.org/0000-0002-5818-5533
Myoung Don OhDepartment of Internal Medicine, Seoul National University College of Medicine, Seoul, Korea.ORCID https://orcid.org/0000-0002-2344-7695
Seoul National University · KRMacrogen (South Korea) · KRIncheon Medical Center · KRSeoul National University Bundang Hospital · KRSeoul National University Hospital · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Novel coronavirus (SARS-CoV-2) is found to cause a large outbreak started from Wuhan since December 2019 in China and SARS-CoV-2 infections have been reported with epidemiological linkage to China in 25 countries until now. We isolated SARS-CoV-2 from the oropharyngeal sample obtained from the patient with the first laboratory-confirmed SARS-CoV-2 infection in Korea. Cytopathic effects of SARS-CoV-2 in the Vero cell cultures were confluent 3 days after the first blind passage of the sample. Coronavirus was confirmed with spherical particle having a fringe reminiscent of crown on transmission electron microscopy. Phylogenetic analyses of whole genome sequences showed that it clustered with other SARS-CoV-2 reported from Wuhan.

Indexed as

BetacoronavirusCoronavirus InfectionsPneumonia, ViralWhole Genome SequencingAdultCOVID-19FemaleHumansMicroscopy, Electron, TransmissionOropharynxPhylogenyRepublic of KoreaSARS-CoV-22019 Novel CoronavirusCultureKoreaMicroscopy, ElectronPhylogeny

Identifiers

PMID32080990
PMCPMC7036342
OpenAlexW3007678386

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.