Evidence map›Paper›PMID 32080965›Full record

ArticleEMBO reports2020

MSCs rescue impaired wound healing in a murine LAD1 model by adaptive responses to low TGF-β1 levels.

Dongsheng Jiang, Karmveer Singh, Jana Muschhammer, Susanne Schatz, Anca Sindrilaru, Evgenia Makrantonaki, Yu Qi, Meinhard Wlaschek, Karin Scharffetter-Kochanek

Open access · hybridAbstract read
In one paragraph

Article in EMBO reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
2.7field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 26 citations in OpenAlex.

  1. Review
  2. Review
  3. Review
  4. Article
  5. Diversity of Fibroblasts and Their Roles in Wound Healing.Cold Spring Harbor perspectives in biology · 2023
    Review
  6. Article
  7. Development and Evaluation ofGels (Basel, Switzerland) · 2022
    Article
  8. Review
  9. Article
  10. Review
  11. Article
  12. Article
  13. Article
  14. Review
  15. Article
  16. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Dongsheng JiangDepartment of Dermatology and Allergic Diseases, University of Ulm, Ulm, Germany.ORCID 0000-0003-0961-2671
Karmveer SinghDepartment of Dermatology and Allergic Diseases, University of Ulm, Ulm, Germany.ORCID 0000-0002-1237-7417
Jana MuschhammerDepartment of Dermatology and Allergic Diseases, University of Ulm, Ulm, Germany.
Susanne SchatzDepartment of Dermatology and Allergic Diseases, University of Ulm, Ulm, Germany.
Anca SindrilaruDepartment of Dermatology and Allergic Diseases, University of Ulm, Ulm, Germany.
Evgenia MakrantonakiDepartment of Dermatology and Allergic Diseases, University of Ulm, Ulm, Germany.
Yu QiDepartment of Dermatology and Allergic Diseases, University of Ulm, Ulm, Germany.
Meinhard WlaschekDepartment of Dermatology and Allergic Diseases, University of Ulm, Ulm, Germany.
Karin Scharffetter-KochanekDepartment of Dermatology and Allergic Diseases, University of Ulm, Ulm, Germany.ORCID 0000-0002-9655-685X
Universität Ulm · DE

Funding

Baden-Württemberg Stiftung (Baden-Württemberg Foundation) P-BWS-ASII/15Deutsche Forschungsgemeinschaft (DFG) SFB1149European Commission (EC) CASCADE HEALTH-FP7-223236German Federal Ministry of Defence E/U2AD/CF521/DF555Universität Ulm (UULM) LSBN.0100
6 · The paper itself

Abstract

Mutations in the CD18 gene encoding the common β-chain of β2 integrins result in impaired wound healing in humans and mice suffering from leukocyte adhesion deficiency syndrome type 1 (LAD1). Transplantation of adipose tissue-derived mesenchymal stem cells (MSCs) restores normal healing of CD18

Indexed as

Leukocyte-Adhesion Deficiency SyndromeMesenchymal Stem CellsAnimalsCell DifferentiationMiceTransforming Growth Factor beta1Wound HealingTransforming Growth Factor beta1chronic woundsenvironment sensingLAD1mesenchymal stem cellsmicroRNA-21

Identifiers

PMID32080965
PMCPMC7132342
OpenAlexW3008774170

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.