Evidence map›Paper›PMID 32080949›Full record

ReviewTraffic (Copenhagen, Denmark)2020

Fluorogen activating protein toolset for protein trafficking measurements.

Lydia A Perkins, Marcel P Bruchez

Abstract readReview
In one paragraph

Review in Traffic (Copenhagen, Denmark), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed.

  1. Unmasking the FACES of membrane bilayers.Nature chemical biology · 2026
    Article
  2. Endosomal Mechanisms in Heart Failure Pathophysiology.Current heart failure reports · 2025
    Review
  3. Article
  4. Combining Machine Learning and Multiplexed,bioRxiv : the preprint server for biology · 2025
    Article
  5. Article
  6. Experimental Approaches to Visualize Effector Protein Translocation During Host-Pathogen Interactions.BioEssays : news and reviews in molecular, cellular and developmental biology · 2025
    Review
  7. Article
  8. Review
  9. Biofilm dispersal patterns revealed using far-red fluorogenic probes.bioRxiv : the preprint server for biology · 2024
    Article
  10. Article
  11. Article
  12. Article
  13. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Lydia A PerkinsSchool of Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.
Marcel P BruchezThe Department of Biological Sciences, Carnegie Mellon, Pittsburgh, Pennsylvania, USA.ORCID 0000-0002-7370-4848

Funding

Targeted fluorescent indicators for endothelial physiology: Ca(II), ROS, NOR01EB017268 · NIBIB · CARNEGIE-MELLON UNIVERSITY · PI BRUCHEZ, MARCEL P, ST CROIX, CLAUDETTE MARIE · 2013 to 2016
$2.5M
Fluorogen Activating Peptide-Based FRET to Quantify FceRI Activation MechanismsR01GM114075 · NIGMS · CARNEGIE-MELLON UNIVERSITY · PI BRUCHEZ, MARCEL P, LIDKE, DIANE · 2015 to 2018
$1.2M
NIBIB NIH HHS R01 EB017268NIBIB NIH HHS R01EB017268NIGMS NIH HHS R01 GM114075NIGMS NIH HHS R01GM114075
6 · The paper itself

Abstract

Throughout the past decade the use of fluorogen activating proteins (FAPs) has expanded with several unique reporter dyes that support a variety of methods to specifically quantify protein trafficking events. The platform's capabilities have been demonstrated in several systems and shared for widespread use. This review will highlight the current FAP labeling techniques for protein traffic measurements and focus on the use of the different designed fluorogenic dyes for selective and specific labeling applications.

Indexed as

Fluorescent DyesProteinsProtein TransportFluorescent DyesProteinsfluorogen activating proteins (FAP)fluorogenic dyeprotein trafficking

Identifiers

PMID32080949
PMCPMC7462100

What OpenQuestion holds

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LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.