Evidence map›Paper›PMID 32080834›Full record

ArticleBritish journal of haematology2020

Mass cytometry identifies expansion of double positive and exhausted T cell subsets in the tumour microenvironment of patients with POEMS syndrome.

Taxiarchis V Kourelis, Dragan Jevremovic, Erik Jessen, Surendra Dasari, Jose C Villasboas, Angela Dispenzieri, Shaji Kumar

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in British journal of haematology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.3field-weighted citation impact, top 41% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Taxiarchis V KourelisDivision of Hematology, Department of Medicine, Mayo Clinic, Rochester, MN, USA.ORCID 0000-0001-8573-9434
Dragan JevremovicDepartment of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN, USA.
Erik JessenDepartment of Health Sciences Research, Mayo Clinic, Rochester, MN, USA.
Surendra DasariDepartment of Health Sciences Research, Mayo Clinic, Rochester, MN, USA.
Jose C VillasboasDivision of Hematology, Department of Medicine, Mayo Clinic, Rochester, MN, USA.
Angela DispenzieriDivision of Hematology, Department of Medicine, Mayo Clinic, Rochester, MN, USA.
Shaji KumarDivision of Hematology, Department of Medicine, Mayo Clinic, Rochester, MN, USA.ORCID 0000-0001-5392-9284
Mayo Clinic in Arizona · USMayo Clinic in Florida · US

Funding

Project 4: Targeting Resistance to T-Cell Directed Therapy in Multiple MyelomaP50CA186781 · NCI · MAYO CLINIC ARIZONA · PI Rafael Fonseca · 2015 to 2026
$25.5M
Mayo ClinicNCI NIH HHS P50 CA186781
6 · The paper itself

Abstract

We sought to dissect the tumour microenvironment in a small cohort (N = 10) of patients with POEMS at diagnosis and after therapy using mass cytometry. We included 10 MGUS patients as controls. We identified 29 immune cell subsets in the CD45

Indexed as

FemaleFlow CytometryHumansMalePOEMS SyndromeT-Lymphocyte SubsetsTumor Microenvironmentimmunohaematologyimmunophenotypingmyelomatumour immunology

Identifiers

PMID32080834
PMCPMC7329569
OpenAlexW3006924202

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.