Evidence map›Paper›PMID 32080789›Full record

ArticleQuality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation2020

Assessing the construct validity and responsiveness of Preference-Based Measures (PBMs) in cataract surgery patients.

Katie Breheny, William Hollingworth, Rebecca Kandiyali, Padraig Dixon, Abi Loose, Pippa Craggs, Mariusz Grzeda, John Sparrow

Open access · hybridAbstract read
In one paragraph

Article in Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
2.7field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 13 citations in OpenAlex.

  1. Sensitivity to change of generic preference-based instruments (EQ-5D-3L, EQ-5D-5L, and HUI3) in the context of treatment for people with prescription-type opioid use disorder in Canada.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2023
    Trial
  2. Trial
  3. Review
  4. Psychometric testing of two respiratory bolt-on items to EQ-5D-5L in patients with obstructive airway diseases.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2025
    Article
  5. Article
  6. Validation and comparison of five preference-based measures among age-related macular degeneration patients: evidence from mainland China.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2022
    Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Katie BrehenyPopulation Health Sciences, Bristol Medical School, University of Bristol, Bristol, UK. katie.breheny@bristol.ac.uk.ORCID http://orcid.org/0000-0001-6886-4049
William HollingworthPopulation Health Sciences, Bristol Medical School, University of Bristol, Bristol, UK.ORCID http://orcid.org/0000-0002-0840-6254
Rebecca KandiyaliPopulation Health Sciences, Bristol Medical School, University of Bristol, Bristol, UK.ORCID http://orcid.org/0000-0001-8566-9536
Padraig DixonPopulation Health Sciences, Bristol Medical School, University of Bristol, Bristol, UK.ORCID http://orcid.org/0000-0001-5285-409X
Abi LooseDepartment of Ophthalmology, Bristol Eye Hospital, Bristol, UK.
Pippa CraggsDepartment of Ophthalmology, Bristol Eye Hospital, Bristol, UK.
Mariusz GrzedaDepartment of Ophthalmology, Bristol Eye Hospital, Bristol, UK.
John SparrowDepartment of Ophthalmology, Bristol Eye Hospital, Bristol, UK.
Bristol Eye Hospital · GBUniversity of Bristol · GBAt Bristol · GB

Funding

Department of Health RP-PG-0611-20013Programme Grants for Applied Research RP-PG-0611-20013
6 · The paper itself

Abstract

purposeThe validity and responsiveness of the EQ-5D-3L in visual conditions has been questioned, inspiring development of a vision 'bolt-on' domain (EQ-5D-3L + VIS). Developments in preference-based measures (PBM) also includes the EQ-5D-5L and the ICECAP-O capability wellbeing measure. This study aimed to examine the construct validity and responsiveness of the EQ-5D-3L, EQ-5D-5L, EQ-5D-3L + VIS and ICECAP-O in cataract surgery patients for the first time, to inform choice of PBM for economic evaluation in this population.

methodsThe analyses used data from the UK Predict-CAT cataract surgery cohort study. PBMs and the Cat-PROM5 [a validated measure of cataract quality of life (QOL)] were completed before surgery and 4-8 weeks after. Construct validity was assessed using correlations and known-group differences evaluated using regression. Responsiveness was evaluated using effect sizes and analysis of variance to compare change scores between groups, defined by patient-reported and clinical outcomes.

resultsThe sample comprised 1315 patients at baseline. No PBMs were associated with visual acuity and only the ICECAP-O (Spearman's rs =  - 0.35), EQ-5D-3L + VIS (rs =  - 0.42) and EQ-5D-5L (Value Set for England rs =  - 0.31) correlated at least moderately with the Cat-PROM5. Effect sizes of change were consistently largest for the EQ-5D-3L + VIS (range 0.34-0.41), followed by the ICECAP-O (range 0.20-0.34). Results indicated no improvement in responsiveness using the EQ-5D-5L (range 0.13-0.16) compared to the EQ-5D-3L (range 0.17-0.20).

conclusionsWhilst no PBMs comprehensively demonstrated evidence of construct validity and responsiveness in cataract surgery patients, the ICECAP-O was the most responsive generic PBM to improvements in QOL. Surprisingly the EQ-5D-5L was not more responsive than the EQ-5D-3L in this setting.

Indexed as

Health StatusAdultAgedCataractCataract ExtractionCohort StudiesCost-Benefit AnalysisFemaleHumansLongitudinal StudiesMaleMiddle AgedPsychometricsQuality of LifeReproducibility of ResultsSurveys and QuestionnairesBolt-onCataractEQ-5DICECAP-OResponsivenessValidity

Identifiers

PMID32080789
PMCPMC7295830
OpenAlexW3008733295

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.