Evidence map›Paper›PMID 32080270›Full record

ArticleScientific reports2020

Controlled Peptide-Mediated Vesicle Fusion Assessed by Simultaneous Dual-Colour Time-Lapsed Fluorescence Microscopy.

Nestor Lopez Mora, Aimee L Boyle, Bart Jan van Kolck, Anouk Rossen, Šárka Pokorná, Alena Koukalová, Radek Šachl, Martin Hof, Alexander Kros

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
2.3field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 43 citations in OpenAlex.

  1. Membrane-Associated Biomolecules for Synthetic Cell Signalling.Chembiochem : a European journal of chemical biology · 2026
    Review
  2. LFC-Lab on a chip · 2026
    Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Review
  12. Calcium-triggered DNA-mediated membrane fusion in synthetic cells.Chemical communications (Cambridge, England) · 2023
    Article
  13. Calcium-triggered DNA-mediated membrane fusion in synthetic cells.bioRxiv : the preprint server for biology · 2023
    Article
  14. Article
  15. Review
  16. Engineering Functional Membrane-Membrane Interfaces by InterSpy.Small (Weinheim an der Bergstrasse, Germany) · 2023
    Article
  17. Review
  18. Nanoparticles for vaccine and gene therapy: Overcoming the barriers to nucleic acid delivery.Wiley interdisciplinary reviews. Nanomedicine and nanobiotechnology · 2022
    Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 2 countries.

Nestor Lopez MoraSupramolecular and Biomaterials Chemistry, Leiden Institute of Chemistry, Leiden University, P.O. Box 9502, 2300, RA, Leiden, The Netherlands.ORCID http://orcid.org/0000-0001-9803-6885
Aimee L BoyleSupramolecular and Biomaterials Chemistry, Leiden Institute of Chemistry, Leiden University, P.O. Box 9502, 2300, RA, Leiden, The Netherlands.
Bart Jan van KolckSupramolecular and Biomaterials Chemistry, Leiden Institute of Chemistry, Leiden University, P.O. Box 9502, 2300, RA, Leiden, The Netherlands.
Anouk RossenSupramolecular and Biomaterials Chemistry, Leiden Institute of Chemistry, Leiden University, P.O. Box 9502, 2300, RA, Leiden, The Netherlands.
Šárka PokornáJ. Heyrovský Institute of Physical Chemistry, Academy of Sciences of the Czech Republic, v.v.i., Dolejškova 2155/3, 182 23, Prague, 8, Czech Republic.
Alena KoukalováJ. Heyrovský Institute of Physical Chemistry, Academy of Sciences of the Czech Republic, v.v.i., Dolejškova 2155/3, 182 23, Prague, 8, Czech Republic.
Radek ŠachlJ. Heyrovský Institute of Physical Chemistry, Academy of Sciences of the Czech Republic, v.v.i., Dolejškova 2155/3, 182 23, Prague, 8, Czech Republic.
Martin HofJ. Heyrovský Institute of Physical Chemistry, Academy of Sciences of the Czech Republic, v.v.i., Dolejškova 2155/3, 182 23, Prague, 8, Czech Republic. martin.hof@jh-inst.cas.cz.
Alexander KrosSupramolecular and Biomaterials Chemistry, Leiden Institute of Chemistry, Leiden University, P.O. Box 9502, 2300, RA, Leiden, The Netherlands. a.kros@chem.leidenuniv.nl.
Leiden University · NLCzech Academy of Sciences, J. Heyrovský Institute of Physical Chemistry · CZ

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We have employed a model system, inspired by SNARE proteins, to facilitate membrane fusion between Giant Unilamellar Vesicles (GUVs) and Large Unilamellar Vesicles (LUVs) under physiological conditions. In this system, two synthetic lipopeptide constructs comprising the coiled-coil heterodimer-forming peptides K

Indexed as

Membrane FusionCholesterolColorDimerizationFluorescence Resonance Energy TransferLipidsLipopeptidesMicroscopy, ConfocalMicroscopy, FluorescencePeptidesPolysorbatesSpectrometry, FluorescenceUnilamellar LiposomesCholesterolLipidsLipopeptidesPeptidesPolysorbatesUnilamellar Liposomes

Identifiers

PMID32080270
PMCPMC7033240
OpenAlexW3008971952

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.