ArticleScientific reports2020
Decimated little brown bats show potential for adaptive change.
Article in Scientific reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 32 papers.
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Who cites it
32 citing papers in PubMed.
- Genomic structural variation rescues a classic biological invader from a population bottleneck.Science advances · 2026Article
- Rapid Evolution in a Coral Population Following a Mass Mortality Event.Evolutionary applications · 2026Article
- Differential Population Responses to White-Nose Syndrome Between Two Michigan Bat Hibernacula Are Not due to Differences in Host Susceptibility.Ecology and evolution · 2025Article
- Low-Coverage Whole-Genome Analysis of Population Structure, Bottlenecks, and Selection in Indiana Bats Before and After White-Nose Syndrome.Molecular ecology · 2025Article
- Variation in Gene Expression Across Infection Status and Elevation in a Hawaiian Honeycreeper.Ecology and evolution · 2025Article
- Article
- Genome-wide diversity and MHC characterisation in a critically endangered freshwater turtle susceptible to disease.Immunogenetics · 2025Article
- Seasonal and comparative evidence of adaptive gene expression in mammalian brain size plasticity.eLife · 2025Article
- High Diversity and Low Genetic Differentiation Among Geographic Populations ofAnimals : an open access journal from MDPI · 2025Article
- A Palearctic view of a bat fungal disease.Conservation biology : the journal of the Society for Conservation Biology · 2025Review
- Transcriptomic evidence of cytokine storm and sepsis in little brown bats exposed to white-nose syndrome.Conservation physiology · 2025Article
- Pseudogymnoascus destructans invasion stage impacts the skin microbial functions of highly vulnerable Myotis lucifugus.FEMS microbiology ecology · 2024Article
- Signals of positive selection in genomes of palearctic Myotis-bats coexisting with a fungal pathogen.BMC genomics · 2024Article
- Impact of putatively beneficial genomic loci on gene expression in little brown bats (Evolutionary applications · 2024Article
- White adipose tissue remodeling in Little Brown Myotis (Myotis lucifugus) with white-nose syndrome.Metabolomics : Official journal of the Metabolomic Society · 2024Article
- Factors influencing the detection and occupancy of little brown bats (Ecology and evolution · 2024Article
- Inferring genetic structure when there is little: population genetics versus genomics of the threatened bat Miniopterus schreibersii across Europe.Scientific reports · 2023Article
- The future of fungi: threats and opportunities.G3 (Bethesda, Md.) · 2022Article
- Active season body mass patterns of little brown and northern myotis bats.Ecology and evolution · 2022Article
- Whole genome resequencing reveals signatures of rapid selection in a virus-affected commercial fishery.Molecular ecology · 2022Article
Corrections and comments
- Erratum issued
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The degree to which species can rapidly adapt is key to survival in the face of climatic and other anthropogenic changes. For little brown bats (Myotis lucifugus), whose populations have experienced declines of over 90% because of the introduced fungal pathogen that causes white-nose syndrome (WNS), survival of the species may ultimately depend upon its capacity for adaptive change. Here, we present evidence of selectively driven change (adaptation), despite dramatic nonadaptive genomic shifts (genetic drift) associated with population declines. We compared the genetic makeups of wild survivors versus non-survivors of WNS, and found significant shifts in allele frequencies of genes associated with regulating arousal from hibernation (GABARB1), breakdown of fats (cGMP-PK1), and vocalizations (FOXP2). Changes at these genes are suggestive of evolutionary adaptation, given that WNS causes bats to arouse with unusual frequency from hibernation, contributing to premature depletion of fat reserves. However, whether these putatively adaptive shifts in allele frequencies translate into sufficient increases in survival for the species to rebound in the face of WNS is unknown.
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