Evidence map›Paper›PMID 32080165›Full record

ArticleTranslational psychiatry2020

Development of an early-warning system for high-risk patients for suicide attempt using deep learning and electronic health records.

Le Zheng, Oliver Wang, Shiying Hao, Chengyin Ye, Modi Liu, Minjie Xia, Alex N Sabo, Liliana Markovic, Frank Stearns, Laura Kanov and 6 more

Open access · goldAbstract read
In one paragraph

Article in Translational psychiatry, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 47 papers, 7 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
47citing papers in PubMed, 7 pooled it
5.7field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

47 citing papers in PubMed, 7 syntheses or guidelines pooled it, 106 citations in OpenAlex.

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  19. Teaching Artificial Intelligence from Conceptual Foundations: A Roadmap for Psychiatry Training Programs.Academic psychiatry : the journal of the American Association of Directors of Psychiatric Residency Training and the Association for Academic Psychiatry · 2025
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 5 institutions in 2 countries.

Le Zheng *Department of Cardiothoracic Surgery, Stanford University, Stanford, CA, USA.
Oliver Wang *HBI Solutions Inc, Palo Alto, CA, USA.
Shiying HaoDepartment of Cardiothoracic Surgery, Stanford University, Stanford, CA, USA.
Chengyin YeDepartment of Health Management, Hangzhou Normal University, Hangzhou, China.
Modi LiuHBI Solutions Inc, Palo Alto, CA, USA.
Minjie XiaHBI Solutions Inc, Palo Alto, CA, USA.
Alex N SaboDepartment of Psychiatry and Behavioral Sciences, Berkshire Medical Center, Pittsfield, MA, USA.
Liliana MarkovicDepartment of Psychiatry and Behavioral Sciences, Berkshire Medical Center, Pittsfield, MA, USA.
Frank StearnsHBI Solutions Inc, Palo Alto, CA, USA.
Laura KanovHBI Solutions Inc, Palo Alto, CA, USA.
Karl G SylvesterDepartment of Surgery, Stanford University, Stanford, CA, USA.
Eric WidenHBI Solutions Inc, Palo Alto, CA, USA.
Doff B McElhinneyDepartment of Cardiothoracic Surgery, Stanford University, Stanford, CA, USA.
Wei ZhangDepartment of Psychiatry, West China Hospital of Sichuan University, Chengdu, China.
Jiayu LiaoDepartment of Bioengineering, Bourns College of Engineering, University of California at Riverside, Riverside, CA, USA.
Xuefeng B LingClinical and Translational Research Program, Betty Irene Moore Children's Heart Center, Lucile Packard Children's Hospital, Palo Alto, CA, USA. bxling@stanford.edu.
Stanford University · USBerkshire Medical Center · USHangzhou Normal University · CNSichuan University · CNWest China Hospital of Sichuan University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Suicide is the tenth leading cause of death in the United States (US). An early-warning system (EWS) for suicide attempt could prove valuable for identifying those at risk of suicide attempts, and analyzing the contribution of repeated attempts to the risk of eventual death by suicide. In this study we sought to develop an EWS for high-risk suicide attempt patients through the development of a population-based risk stratification surveillance system. Advanced machine-learning algorithms and deep neural networks were utilized to build models with the data from electronic health records (EHRs). A final risk score was calculated for each individual and calibrated to indicate the probability of a suicide attempt in the following 1-year time period. Risk scores were subjected to individual-level analysis in order to aid in the interpretation of the results for health-care providers managing the at-risk cohorts. The 1-year suicide attempt risk model attained an area under the curve (AUC ROC) of 0.792 and 0.769 in the retrospective and prospective cohorts, respectively. The suicide attempt rate in the "very high risk" category was 60 times greater than the population baseline when tested in the prospective cohorts. Mental health disorders including depression, bipolar disorders and anxiety, along with substance abuse, impulse control disorders, clinical utilization indicators, and socioeconomic determinants were recognized as significant features associated with incident suicide attempt.

Indexed as

Deep LearningSuicide, AttemptedElectronic Health RecordsHumansProspective StudiesRetrospective StudiesRisk FactorsUnited States

Identifiers

PMID32080165
PMCPMC7033212
OpenAlexW3007372240

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.