Evidence map›Paper›PMID 32079666›Full record

ArticleThorax2020

Non-communicable respiratory disease and air pollution exposure in Malawi: a prospective cohort study.

Sarah Rylance, Chris Jewell, Andrew Naunje, Frank Mbalume, John D Chetwood, Rebecca Nightingale, Lindsay Zurba, Graham Flitz, Stephen B Gordon, Maia Lesosky and 2 more

Abstract read
In one paragraph

Article in Thorax, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Trial
  5. Article
  6. Review
  7. Article
  8. Small Airway Disease in Pre-COPD and Early COPD: Insights Into the Pulmonary "Silent Zone".International journal of chronic obstructive pulmonary disease · 2026
    Review
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
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  17. Household air pollution and COPD: cause and effect or confounding by other aspects of poverty?The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease · 2022
    Review
  18. Long-Term PMInternational journal of environmental research and public health · 2022
    Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Sarah RylanceDepartment of Clinical Sciences, Liverpool School of Tropical Medicine, Liverpool, UK.ORCID 0000-0001-6459-9073
Chris JewellCHICAS, University of Lancaster, Lancaster, UK.
Andrew NaunjeLung Health Group, Malawi Liverpool Wellcome Trust Clinical Research Programme, Blantyre, Malawi.
Frank MbalumeLung Health Group, Malawi Liverpool Wellcome Trust Clinical Research Programme, Blantyre, Malawi.
John D ChetwoodJohn Hunter Hospital, New Lambton Heights, New South Wales, Australia.
Rebecca NightingaleDepartment of Clinical Sciences, Liverpool School of Tropical Medicine, Liverpool, UK.
Lindsay ZurbaEducation for Health Africa, Vereeniging, South Africa.
Graham FlitzSchool of Public Health, University of California, Berkeley, California, USA.
Stephen B GordonDepartment of Clinical Sciences, Liverpool School of Tropical Medicine, Liverpool, UK.
Maia LesoskyDivision of Epidemiology and Biostatistics, School of Public Health and Family Medicine, University of Cape Town, Rondebosch, Cape Town, South Africa.
John R BalmesSchool of Public Health, University of California, Berkeley, California, USA.
Kevin MortimerDepartment of Clinical Sciences, Liverpool School of Tropical Medicine, Liverpool, UK kevin.mortimer@lstmed.ac.uk.ORCID 0000-0002-8118-8871

Funding

Cluster Randomized Controlled Trial of an Advanced Stove to Reduce Risk of COPDR56ES023566 · NIEHS · UNIVERSITY OF CALIFORNIA BERKELEY · PI BALMES, JOHN R · 2014 to 2014
$120k
Medical Research Council MR/K006533/1Medical Research Council MR/L002515/1Medical Research Council MR/P022006/1NIEHS NIH HHS R56 ES023566Wellcome Trust
6 · The paper itself

Abstract

rationaleThere are no population-based studies from sub-Saharan Africa describing longitudinal lung function in adults.

objectivesTo explore the lung function trajectories and their determinants, including the effects of air pollution exposures and the cleaner-burning biomass-fuelled cookstove intervention of the Cooking and Pneumonia Study (CAPS), in adults living in rural Malawi.

methodsWe assessed respiratory symptoms and exposures, spirometry and measured 48-hour personal exposure to fine particulate matter (PM MEASUREMENTS AND MAIN

resultsWe recruited 1481 adults, mean (SD) age 43.8 (17.8) years, including 523 participants from CAPS households (271 intervention; 252 controls), and collected multiple spirometry and air pollution measurements for 654 (44%) and 929 (63%), respectively. Compared with Global Lung Function Initiative African-American reference ranges, mean (SD) FEV

conclusionsWe did not observe accelerated lung function decline in this cohort of Malawian adults, compared with that reported in healthy, non-smoking populations from high-income countries; this suggests that the lung function deficits we measured in adulthood may have origins in early life.

Indexed as

AdultAir Pollution, IndoorCarbon MonoxideCookingEnvironmental ExposureEnvironmental MonitoringFemaleForced Expiratory VolumeHumansLongitudinal StudiesLungMalawiMaleMiddle AgedParticulate MatterProspective StudiesCarbon MonoxideParticulate Matterclinical Epidemiologylung Physiology

Identifiers

PMID32079666
PMCPMC7063402

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.