ArticleTissue engineering. Part A2020
Bioprinting 101: Design, Fabrication, and Evaluation of Cell-Laden 3D Bioprinted Scaffolds.
Article in Tissue engineering. Part A, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 72 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
72 citing papers in PubMed, 1 synthesis or guideline pooled it.
- 3D Printing Techniques and Their Applications to Organ-on-a-Chip Platforms: A Systematic Review.Sensors (Basel, Switzerland) · 2021Pooled it
- dECM bioinks for 3D bioprinted tumor models: Advances, challenges, and drug screening.iScience · 2026Review
- 3D bioprinting for cancer modeling and drug screening.Biomarker research · 2026Review
- Developing a Clinically Practical Biomaterial Platform for Endogenous Liver Regeneration.Gels (Basel, Switzerland) · 2026Review
- Influence of Boron Nitride Nanosheets on the Properties of Gelatin-Chitosan Bioinks for Extrusion-Based 3D Bioprinting.Biopolymers · 2026Article
- The Promise of 3D Biomaterial Bioprinting for Wound-Healing and Skin Tissue Restoration.Life (Basel, Switzerland) · 2026Review
- Fiber-integrated hydrogels: a versatile platform to improve structural and biological performance in 3D biofabrication.Materials today. Bio · 2026Review
- 3D biofabricated in vitro models as new approach methodologies for animal alternatives.npj biomedical innovations · 2026Review
- Data-Driven Printability Modeling of Hydrogels for Precise Direct Ink Writing Based on Rheological Properties.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Article
- 3D Printing with Tragacanth-Gum-Based Bioinks: A New Frontier in Bioprinting Materials.Gels (Basel, Switzerland) · 2026Review
- Hybrid Bioprinting for functionally graded tissue engineering constructs with patterned and localized biochemical signals.Advanced composites and hybrid materials · 2026Article
- 3D Bioprinting Functional Engineered Heart Tissues.International journal of molecular sciences · 2025Review
- Review
- Microgel-based bioink for extrusion-based 3D bioprinting and its applications in tissue engineering.Bioactive materials · 2025Review
- Machine Learning-Enhanced Optimization for High-Throughput Precision in Cellular Droplet Bioprinting.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025Article
- Comparative Analysis of Electron Microscopy Techniques for Hydrogel Microarchitecture Characterization: SEM, Cryo-SEM, ESEM, and TEM.ACS omega · 2025Article
- Hydrogel-Based Bioinks for Coaxial and Triaxial Bioprinting: A Review of Material Properties, Printing Techniques, and Applications.Polymers · 2025Review
- Harnessing native blueprints for designing bioinks to bioprint functional cardiac tissue.iScience · 2025Review
- Effects of Polyhydroxybutyrate-co-hydroxyvalerate Microparticle Loading on Rheology, Microstructure, and Processability of Hydrogel-Based Inks for Bioprinted and Moulded Scaffolds.Gels (Basel, Switzerland) · 2025Article
- Characterization and Machine Learning-Driven Property Prediction of a Novel Hybrid Hydrogel Bioink Considering Extrusion-Based 3D Bioprinting.Gels (Basel, Switzerland) · 2025Article
12 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
3D bioprinting is an additive manufacturing technique that recapitulates the native architecture of tissues. This is accomplished through the precise deposition of cell-containing bioinks. The spatiotemporal control over bioink deposition permits for improved communication between cells and the extracellular matrix, facilitates fabrication of anatomically and physiologically relevant structures. The physiochemical properties of bioinks, before and after crosslinking, are crucial for bioprinting complex tissue structures. Specifically, the rheological properties of bioinks determines printability, structural fidelity, and cell viability during the printing process, whereas postcrosslinking of bioinks are critical for their mechanical integrity, physiological stability, cell survival, and cell functions. In this review, we critically evaluate bioink design criteria, specifically for extrusion-based 3D bioprinting techniques, to fabricate complex constructs. The effects of various processing parameters on the biophysical and biochemical characteristics of bioinks are discussed. Furthermore, emerging trends and future directions in the area of bioinks and bioprinting are also highlighted. Graphical abstract [Figure: see text] Impact statement Extrusion-based 3D bioprinting is an emerging additive manufacturing approach for fabricating cell-laden tissue engineered constructs. This review critically evaluates bioink design criteria to fabricate complex tissue constructs. Specifically, pre- and post-printing evaluation approaches are described, as well as new research directions in the field of bioink development and functional bioprinting are highlighted.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.