Observational studyNutrients2020
Protein-Related Dietary Parameters and Frailty Status in Older Community-Dwellers across Different Frailty Instruments.
Observational study in Nutrients, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
23 citing papers in PubMed, 3 syntheses or guidelines pooled it, 38 citations in OpenAlex.
- Pooled it
- Protein Intake and Frailty in Older Adults: A Systematic Review and Meta-Analysis of Observational Studies.Nutrients · 2022Pooled it
- Association between Dysphagia and Frailty in Older Adults: A Systematic Review and Meta-Analysis.Nutrients · 2022Pooled it
- Non-linear associations and threshold effects of oxidative balance score and composite dietary antioxidant index on frailty risk in patients with cardiovascular-kidney-metabolic syndrome.Frontiers in nutrition · 2025Article
- Late-life isoleucine restriction promotes physiological and molecular signatures of healthy aging.bioRxiv : the preprint server for biology · 2024Article
- The rosetta stone of successful ageing: does oral health have a role?Biogerontology · 2023Review
- Associations between Low-Carbohydrate Diets and Low-Fat Diets with Frailty in Community-Dwelling Aging Chinese Adults.Nutrients · 2023Article
- Lysophospholipids and branched chain amino acids are associated with aging: a metabolomics-based study of Chinese adults.European journal of medical research · 2023Article
- Are Skeletal Muscle Changes during Prolonged Space Flights Similar to Those Experienced by Frail and Sarcopenic Older Adults?Life (Basel, Switzerland) · 2022Review
- Association between Branched-Chain Amino Acid Intake and Physical Function among Chinese Community-Dwelling Elderly Residents.Nutrients · 2022Article
- Physiological Systems in Promoting Frailty.Comprehensive Physiology · 2022Review
- The Association of Nutrition Quality with Frailty Syndrome among the Elderly.International journal of environmental research and public health · 2022Article
- The Flexibility of Physio-Cognitive Decline Syndrome: A Longitudinal Cohort Study.Frontiers in public health · 2022Article
- Relationship between Oral Hypofunction, and Protein Intake: A Cross-Sectional Study in Local Community-Dwelling Adults.Nutrients · 2021Article
- Association between Dietary Patterns and Frailty Prevalence in Shanghai Suburban Elders: A Cross-Sectional Study.International journal of environmental research and public health · 2021Article
- Article
- Functional Frailty, Dietary Intake, and Risk of Malnutrition. Are Nutrients Involved in Muscle Synthesis the Key for Frailty Prevention?Nutrients · 2021Article
- Uremic Sarcopenia and Its Possible Nutritional Approach.Nutrients · 2021Review
- The regulation of healthspan and lifespan by dietary amino acids.Translational medicine of aging · 2021Article
- Lifelong restriction of dietary branched-chain amino acids has sex-specific benefits for frailty and lifespan in mice.Nature aging · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors at 4 institutions in 2 countries.
Funding
Abstract
The present study investigated the associations between frailty status and (a) daily protein intake, (b) daily body weight-adjusted protein intake, (c) branched-chain amino acid (BCAA) consumption, (d) evenness of protein distribution across main meals, (e) number of daily meals providing at least 30 g of protein, and (f) number of daily meals providing at least 0.4 g protein/kg of body weight in community-dwelling older adults. The relationship between frailty status and protein-related dietary parameters was explored across different frailty assessment tools. Two hundred older adults were enrolled in the study. Participant frailty status was determined according to a modified Fried's frailty phenotype (mFP), the FRAIL scale, and the Study of Osteoporotic Fracture (SOF) index. Diet was assessed by 24-h dietary recall, while diet composition was estimated using a nutritional software. A frailty instrument-dependent relationship was observed between frailty status and protein-related dietary parameters. Protein consumption was associated with frailty status only in participants identified as frail according to the mFP. In addition, protein and BCAA intake was found to be greater in robust and pre-frail participants relative to their frail counterparts. Our findings suggest that the association between frailty and protein-related dietary parameters is tool dependent. Specifically, protein and BCAA consumption appears to be lower only in older adults identified as frail by the mFP.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.