Evidence map›Paper›PMID 32079312›Full record

ArticlePathogens (Basel, Switzerland)2020

Foot-and-Mouth Disease Virus Lacking the Leader Protein and Containing Two Negative DIVA Markers (FMDV LL3B3D A

Michael Eschbaumer, Veronika Dill, Jolene C Carlson, Jonathan Arzt, Carolina Stenfeldt, Peter W Krug, John M Hardham, Jacob E Stegner, Luis L Rodriguez, Elizabeth Rieder

Open access · goldAbstract read
In one paragraph

Article in Pathogens (Basel, Switzerland), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.3field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 9 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 2 countries.

Michael EschbaumerInstitute of Diagnostic Virology, Friedrich-Loeffler-Institut, Greifswald - Insel Riems 17493, Germany.
Veronika DillInstitute of Diagnostic Virology, Friedrich-Loeffler-Institut, Greifswald - Insel Riems 17493, Germany.
Jolene C CarlsonInstitute of Diagnostic Virology, Friedrich-Loeffler-Institut, Greifswald - Insel Riems 17493, Germany.
Jonathan ArztPlum Island Animal Disease Center, USDA/ARS, Orient, NY 11957, USA.
Carolina StenfeldtPlum Island Animal Disease Center, USDA/ARS, Orient, NY 11957, USA.
Peter W KrugPlum Island Animal Disease Center, USDA/ARS, Orient, NY 11957, USA.
John M HardhamZoetis Inc., Kalamazoo, MI 49007, USA.
Jacob E StegnerZoetis Inc., Kalamazoo, MI 49007, USA.
Luis L RodriguezPlum Island Animal Disease Center, USDA/ARS, Orient, NY 11957, USA.
Elizabeth RiederPlum Island Animal Disease Center, USDA/ARS, Orient, NY 11957, USA.
Plum Island Animal Disease Center · USFriedrich-Loeffler-Institut · DEZoetis (United States) · USKansas State University · US

Funding

Agricultural Research Service 58-8064-7-007-F
6 · The paper itself

Abstract

Inactivated whole-virus vaccines are widely used for the control of foot-and-mouth disease (FMD). Their production requires the growth of large quantities of virulent FMD virus in biocontainment facilities, which is expensive and carries the risk of an inadvertent release of virus. Attenuated recombinant viruses lacking the leader protease coding region have been proposed as a safer alternative for the production of inactivated FMD vaccines (Uddowla et al., 2012,

Indexed as

attenuatedDIVAfoot-and-mouth disease virusleaderlessmarker virus

Identifiers

PMID32079312
PMCPMC7168223
OpenAlexW3008947389

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.