Evidence map›Paper›PMID 32079202›Full record

ReviewBiomolecules2020

Brain Cytoplasmic RNAs in Neurons: From Biosynthesis to Function.

Younghoon Lee, Hee-Seung Lee, Meehyein Kim, Heegwon Shin

Open access · goldAbstract readReview
In one paragraph

Review in Biomolecules, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.5field-weighted citation impact, top 45% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 8 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Younghoon LeeDepartment of Chemistry, Korea Advanced Institute of Science and Technology (KAIST), Daejeon 34141, Korea.
Hee-Seung LeeDepartment of Chemistry, Korea Advanced Institute of Science and Technology (KAIST), Daejeon 34141, Korea.
Meehyein KimInnovative Target Research Center, Korea Research Institute of Chemical Technology, Daejeon 34114, Korea.
Heegwon ShinDepartment of Chemistry, Korea Advanced Institute of Science and Technology (KAIST), Daejeon 34141, Korea.
Korea Advanced Institute of Science and Technology · KRKorea Research Institute of Chemical Technology · KR

Funding

National Research Foundation of Korea 2017R1A6A3A11031308National Research Foundation of Korea 2018R1A5A1025208National Research Foundation of Korea 2019R1H1A2039730
6 · The paper itself

Abstract

Flexibility in signal transmission is essential for high-level brain function. This flexibility is achieved through strict spatial and temporal control of gene expression in neurons. Given the key regulatory roles of a variety of noncoding RNAs (ncRNAs) in neurons, studying neuron-specific ncRNAs provides an important basis for understanding molecular principles of brain function. This approach will have wide use in understanding the pathogenesis of brain diseases and in the development of therapeutic agents in the future. Brain cytoplasmic RNAs (BC RNAs) are a leading paradigm for research on neuronal ncRNAs. Since the first confirmation of brain-specific expression of BC RNAs in 1982, their investigation has been an area of active research. In this review, we summarize key studies on the characteristics and functions of BC RNAs in neurons.

Indexed as

AnimalsBrainBrain DiseasesCytoplasmGene ExpressionGene Expression RegulationHumansNeuronsProtein BiosynthesisRNA StabilityRNA, UntranslatedTranscription, GeneticRNA, Untranslatedbrain cytoplasmic RNAsneuronneuronal plasticitynoncoding RNAtranslation inhibition

Identifiers

PMID32079202
PMCPMC7072442
OpenAlexW3005625833

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.