Evidence map›Paper›PMID 32078963›Full record

ArticleNeural networks : the official journal of the International Neural Network Society2020

PET image super-resolution using generative adversarial networks.

Tzu-An Song, Samadrita Roy Chowdhury, Fan Yang, Joyita Dutta

Abstract read
In one paragraph

Article in Neural networks : the official journal of the International Neural Network Society, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  8. Review
  9. PET image denoising based on denoising diffusion probabilistic model.European journal of nuclear medicine and molecular imaging · 2024
    Article
  10. Review
  11. Brain imaging with portable low-field MRI.Nature reviews bioengineering · 2023
    Article
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  19. Article
  20. Noise2Void: unsupervised denoising of PET images.Physics in medicine and biology · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Tzu-An SongDepartment of Electrical and Computer Engineering, University of Massachusetts Lowell, Lowell, MA, United States of America.
Samadrita Roy ChowdhuryDepartment of Electrical and Computer Engineering, University of Massachusetts Lowell, Lowell, MA, United States of America.
Fan YangDepartment of Electrical and Computer Engineering, University of Massachusetts Lowell, Lowell, MA, United States of America.
Joyita DuttaDepartment of Electrical and Computer Engineering, University of Massachusetts Lowell, Lowell, MA, United States of America; Gordon Center for Medical Imaging, Massachusetts General Hospital and Harvard Medical School, Boston, MA, United States of America; Geriatric Research, Education and Clinical Center, Edith Nourse Rogers Memorial Veterans Hospital, Bedford, MA, United States of America. Electronic address: dutta.joyita@mgh.harvard.edu.

Funding

Tau Quantitation in AD with High Resolution MRI and PETK01AG050711 · NIA · MASSACHUSETTS GENERAL HOSPITAL · PI DUTTA, JOYITA · 2015 to 2019
$650k
NIA NIH HHS K01 AG050711
6 · The paper itself

Abstract

The intrinsically low spatial resolution of positron emission tomography (PET) leads to image quality degradation and inaccurate image-based quantitation. Recently developed supervised super-resolution (SR) approaches are of great relevance to PET but require paired low- and high-resolution images for training, which are usually unavailable for clinical datasets. In this paper, we present a self-supervised SR (SSSR) technique for PET based on dual generative adversarial networks (GANs), which precludes the need for paired training data, ensuring wider applicability and adoptability. The SSSR network receives as inputs a low-resolution PET image, a high-resolution anatomical magnetic resonance (MR) image, spatial information (axial and radial coordinates), and a high-dimensional feature set extracted from an auxiliary CNN which is separately-trained in a supervised manner using paired simulation datasets. The network is trained using a loss function which includes two adversarial loss terms, a cycle consistency term, and a total variation penalty on the SR image. We validate the SSSR technique using a clinical neuroimaging dataset. We demonstrate that SSSR is promising in terms of image quality, peak signal-to-noise ratio, structural similarity index, contrast-to-noise ratio, and an additional no-reference metric developed specifically for SR image quality assessment. Comparisons with other SSSR variants suggest that its high performance is largely attributable to simulation guidance.

Indexed as

Neural Networks, ComputerImage Processing, Computer-AssistedMagnetic Resonance ImagingPositron-Emission TomographySignal-To-Noise RatioCNNGANMultimodality imagingPETSelf-supervisedSuper-resolution

Identifiers

PMID32078963
PMCPMC7136141

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.