Evidence map›Paper›PMID 32078374›Full record

ArticleCirculation. Arrhythmia and electrophysiology2020

Noninvasive Assessment of Complexity of Atrial Fibrillation: Correlation With Contact Mapping and Impact of Ablation.

Miguel Rodrigo, Andreu M Climent, Ismael Hernández-Romero, Alejandro Liberos, Tina Baykaner, Albert J Rogers, Mahmood Alhusseini, Paul J Wang, Francisco Fernández-Avilés, Maria S Guillem and 2 more

Abstract readMulticenter Study
In one paragraph

Article in Circulation. Arrhythmia and electrophysiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed.

  1. Article
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  3. Observational
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  9. 2024 European Heart Rhythm Association/Heart Rhythm Society/Asia Pacific Heart Rhythm Society/Latin American Heart Rhythm Society expert consensus statement on catheter and surgical ablation of atrial fibrillation.Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology · 2024
    Article
  10. Quantifying a spectrum of clinical response in atrial tachyarrhythmias using spatiotemporal synchronization of electrograms.Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology · 2023
    Article
  11. Electrocardiographic imaging in the atria.Medical & biological engineering & computing · 2023
    Review
  12. Article
  13. Article
  14. Future Directions for Mapping Atrial Fibrillation.Arrhythmia & electrophysiology review · 2022
    Review
  15. Article
  16. Is there rule to the chaos: Defining stable patterns in atrial fibrillation.Journal of cardiovascular electrophysiology · 2021
    Article
  17. Article
  18. Review
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Miguel RodrigoITACA Institute, Universitat Politècnica de València (M.R., A.M.C., A.L., M.S.G.).
Andreu M ClimentITACA Institute, Universitat Politècnica de València (M.R., A.M.C., A.L., M.S.G.).
Ismael Hernández-RomeroCardiology Department, Hospital General Universitario Gregorio Marañón, Instituto de Investigacion Sanitaria Gregorio Marañon (IISGM) (M.R., A.M.C., I.H.-R., A.L., F.F.-A., F.A.), Madrid, Spain.
Alejandro LiberosITACA Institute, Universitat Politècnica de València (M.R., A.M.C., A.L., M.S.G.).
Tina BaykanerCardiac Electrophysiology and Arrhythmia Service, Division of Cardiovascular Medicine, Stanford University School of Medicine, CA (M.R., T.B., A.J.R., M.A., P.J.W., S.M.N.).
Albert J RogersCardiac Electrophysiology and Arrhythmia Service, Division of Cardiovascular Medicine, Stanford University School of Medicine, CA (M.R., T.B., A.J.R., M.A., P.J.W., S.M.N.).
Mahmood AlhusseiniCardiac Electrophysiology and Arrhythmia Service, Division of Cardiovascular Medicine, Stanford University School of Medicine, CA (M.R., T.B., A.J.R., M.A., P.J.W., S.M.N.).
Paul J WangCardiac Electrophysiology and Arrhythmia Service, Division of Cardiovascular Medicine, Stanford University School of Medicine, CA (M.R., T.B., A.J.R., M.A., P.J.W., S.M.N.).
Francisco Fernández-AvilésCardiology Department, Hospital General Universitario Gregorio Marañón, Instituto de Investigacion Sanitaria Gregorio Marañon (IISGM) (M.R., A.M.C., I.H.-R., A.L., F.F.-A., F.A.), Madrid, Spain.
Maria S GuillemITACA Institute, Universitat Politècnica de València (M.R., A.M.C., A.L., M.S.G.).
Sanjiv M NarayanCardiac Electrophysiology and Arrhythmia Service, Division of Cardiovascular Medicine, Stanford University School of Medicine, CA (M.R., T.B., A.J.R., M.A., P.J.W., S.M.N.).
Felipe AtienzaCardiology Department, Hospital General Universitario Gregorio Marañón, Instituto de Investigacion Sanitaria Gregorio Marañon (IISGM) (M.R., A.M.C., I.H.-R., A.L., F.F.-A., F.A.), Madrid, Spain.

Funding

The Dynamics of Human Atrial FibrillationR01HL083359 · NHLBI · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI Sanjiv M Narayan · 2008 to 2026
$7.9M
The Maintenance of Human Atrial FibrillationK24HL103800 · NHLBI · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI NARAYAN, SANJIV M · 2010 to 2019
$1.9M
Impact of intermittent hypoxia on ventilatory drive and apnea severityR01HL085537 · NHLBI · WAYNE STATE UNIVERSITY · PI MATEIKA, JASON H. · 2007 to 2010
$1.5M
Deep Neural Networks To Treat Atrial FibrillationK23HL145017 · NHLBI · STANFORD UNIVERSITY · PI BAYKANER, TINA · 2019 to 2023
$968k
NHLBI NIH HHS K23 HL145017NHLBI NIH HHS K24 HL103800NHLBI NIH HHS R01 HL083359NHLBI NIH HHS R01 HL085537
6 · The paper itself

Abstract

backgroundIt is difficult to noninvasively phenotype atrial fibrillation (AF) in a way that reflects clinical end points such as response to therapy. We set out to map electrical patterns of disorganization and regions of reentrant activity in AF from the body surface using electrocardiographic imaging, calibrated to panoramic intracardiac recordings and referenced to AF termination by ablation.

methodsBi-atrial intracardiac electrograms of 47 patients with AF at ablation (30 persistent, 29 male, 63±9 years) were recorded with 64-pole basket catheters and simultaneous 57-lead body surface ECGs. Atrial epicardial electrical activity was reconstructed and organized sites were invasively and noninvasively tracked in 3-dimension using phase singularity. In a subset of 17 patients, sites of AF organization were targeted for ablation.

resultsBody surface mapping showed greater AF organization near intracardially detected drivers than elsewhere, both in phase singularity density (2.3±2.1 versus 1.9±1.6;

conclusionsAF complexity tracked noninvasively correlates well with organized and disorganized regions detected by panoramic intracardiac mapping and correlates with the acute outcome by ablation. This approach may assist in bedside monitoring of therapy or in improving the efficacy of ongoing ablation procedures.

Indexed as

Atrial FibrillationBody Surface Potential MappingCatheter AblationElectrophysiologic Techniques, CardiacFemaleFollow-Up StudiesHeart AtriaHeart Conduction SystemHeart RateHumansMaleMiddle AgedProspective StudiesSignal Processing, Computer-AssistedTime FactorsTreatment Outcomeatrial fibrillationelectrocardiographygoalmalepulmonary vein

Identifiers

PMID32078374
PMCPMC7508259

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.