ArticleAmerican journal of public health2020
Alcohol Industry Involvement in the Moderate Alcohol and Cardiovascular Health Trial.
Article in American journal of public health, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
21 citing papers in PubMed, 2 syntheses or guidelines pooled it, 40 citations in OpenAlex.
- From the tobacco industry's uses of science for public relations purposes to the alcohol industry: Tobacco industry documents study.Drug and alcohol review · 2023Pooled it
- Alcohol consumption in relation to cardiovascular diseases and mortality: a systematic review of Mendelian randomization studies.European journal of epidemiology · 2022Pooled it
- Evidence triangulation in health research.European journal of epidemiology · 2025Article
- Labelling the debate: a thematic analysis of alcohol industry submissions to the EU consultation on alcohol health warnings in Ireland.Globalization and health · 2025Article
- Randomised study of the effects of sense of entitlement and conflict of interest contrarianism on researcher decision-making to work with the alcohol industry.BMC public health · 2024Article
- Evolution of the major alcohol companies key global policy vehicle through the prism of tax records 2011-19.Globalization and health · 2023Article
- Alcohol and Public Health: Failure and Opportunity.The Milbank quarterly · 2023Article
- Distilling the distillers: examining the political activities of the Distilled Spirits Council of the United States.Globalization and health · 2023Article
- The emperor has no clothes: a synthesis of findings from the Transformative Research on the Alcohol industry, Policy and Science research programme.Addiction (Abingdon, England) · 2023Review
- "Using information to shape perception": tobacco industry documents study of the evolution of Corporate Affairs in the Miller Brewing Company.Globalization and health · 2022Article
- The alcohol industry, the tobacco industry, and excise taxes in the US 1986-89: new insights from the tobacco documents.BMC public health · 2022Article
- The Ubiquitous Experience of Alcohol Industry Involvement in Science: Findings From a Qualitative Interview Study.Journal of studies on alcohol and drugs · 2022Article
- Mendelian randomization.Nature reviews. Methods primers · 2022Article
- The 'snowball effect': short and long-term consequences of early career alcohol industry research funding.Addiction research & theory · 2022Article
- Alcohol, cardiovascular disease and industry funding: A co-authorship network analysis of systematic reviews.Social science & medicine (1982) · 2021Article
- The positive association between physical activity and alcohol use in African American adults.Preventive medicine reports · 2021Article
- Integrating genomics with biomarkers and therapeutic targets to invigorate cardiovascular drug development.Nature reviews. Cardiology · 2021Review
- Alcohol marketing versus public health: David and Goliath?Globalization and health · 2021Article
- Declared funding and authorship by alcohol industry actors in the scientific literature: a bibliometric study.European journal of public health · 2020Article
- Mendel's laws, Mendelian randomization and causal inference in observational data: substantive and nomenclatural issues.European journal of epidemiology · 2020Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 1 country.
Funding
Abstract
The National Institutes of Health stopped the worldwide Moderate Alcohol and Cardiovascular Health (MACH) trial in 2018 because of institutional failings that led to the biased design of this major study. Drawing on e-mail correspondence among officials, researchers, and alcohol companies, we provide the first, to our knowledge, detailed analysis of alcohol industry involvement in the MACH trial.Alcohol companies agreed to fund the MACH trial to advance their commercial interests rather than to help answer a major scientific question. Alcohol industry executives seized opportunities presented by discussions of the MACH trial to try to influence this study and wider public health, research, and policy decision-making.The process of soliciting research funding from corporations, which included convincing alcohol companies that the study design supported their commercial interests, was intrinsically biased. Thus, the three parties-research funding officials, researchers, and industry executives-coproduced the biased trial design. A detailed understanding of this episode will be helpful in advancing efforts to protect public health research from biases associated with corporate donations.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.