Evidence map›Paper›PMID 32078026›Full record

ArticleEuropean archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery2020

Is drug consumption correlated with benign paroxysmal positional vertigo (BPPV) recurrence?

Pasqualina Maria Picciotti, Tiziana Di Cesare, Laura Tricarico, Eugenio De Corso, Jacopo Galli, Gaetano Paludetti

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Article in European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.9field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 12 citations in OpenAlex.

  1. Article
  2. Prevalence of self-perceived audiovestibular symptoms in Egyptian COVID-19 patients.The Journal of the Egyptian Public Health Association · 2023
    Article
  3. Article
  4. Article
  5. Onset and resolution failure of recurrent benign paroxysmal positional vertigo: the role of cervical range of motion.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2022
    Article
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 2 countries.

Pasqualina Maria PicciottiENT and Head Neck Surgery Department, Catholic University, Rome, Italy.
Tiziana Di CesarePhysician Undergoing Specialised Medical Training (ENT and Head Neck Surgery), Catholic University, Rome, Italy. Tizianadicesare90@gmail.com.ORCID http://orcid.org/0000-0001-9756-1880
Laura TricaricoPhysician Undergoing Specialised Medical Training (ENT and Head Neck Surgery), Catholic University, Rome, Italy.
Eugenio De CorsoENT and Head Neck Surgery Department, Catholic University, Rome, Italy.
Jacopo GalliENT and Head Neck Surgery Department, Catholic University, Rome, Italy.
Gaetano PaludettiENT and Head Neck Surgery Department, Catholic University, Rome, Italy.
Università Cattolica del Sacro Cuore · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundBenign paroxysmal positional vertigo (BPPV) is the most common cause of peripheral vertigo and its recurrence is fairly common. Several studies correlated the pathophysiological role of different comorbidities-such as diabetes, osteoporosis, vascular, psychiatric and autoimmune diseases-in the development and recurrence of BPPV. The aim of this study is to analyse the pharmacological history of patients with idiopathic BPPV in relation to the risk of developing recurrence.

methodsData regarding 715 patients aged 12 to 87 years (62.7 ± 14) with non-traumatic BPPV were retrospectively evaluated. These refer to the Vestibular Service, day clinic, and were collected over a 4-year period, between 2014 and 2018.

resultsRecurrence of BPPV was observed in 220/715 patients (30.76%). A statistically significant correlation (p < 0.006) between recurrence and drug consumption was observed for SNC agents (p = 0.0001), vitamin D (p = 0.0005), PPI (p = 0.0007), thyroid hormones (p = 0.0011), and antihypertensives in single use (p = 0.0031). On the contrary, cholesterol-lowering statin drugs, hypoglycaemic agents, antiplatelet medication, estroprogestins and combination of two or more antihypertensives did not show significant correlation.

conclusionSpecific classes of drugs are significantly associated with recurrence: antihypertensive therapy with a singular agent, central nervous system agents, PPIs, vitamin D and thyroid hormones. On the other hand, the lack of correlation between some drugs and recurrence could be linked to the effectiveness of therapy in controlling hypertension, dyslipidaemia and diabetes. Pharmacological history is an essential tool to identify patients at risk of BPPV recurrence.

Indexed as

Benign Paroxysmal Positional VertigoPharmaceutical PreparationsAdolescentAdultAgedAged, 80 and overChildComorbidityHumansMiddle AgedRecurrenceRetrospective StudiesYoung AdultPharmaceutical PreparationsBenign paroxysmal positional vertigoBPPVDrugsRecurrenceRecurrent positional vertigoVertigo

Identifiers

PMID32078026
OpenAlexW3008703005

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.