Evidence map›Paper›PMID 32077999›Full record

ArticleIntensive care medicine2020

Alternative RNA splicing and alternative transcription start/end in acute respiratory distress syndrome.

Alger M Fredericks, Li Juan Wang, William G Fairbrother, Alfred Ayala, Sean F Monaghan

Abstract readLetter
PubMed Full text at PMC Publisher
In one paragraph

Article in Intensive care medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Alternative splicing of toll-like receptor pathway mRNAs in lung immune cells from patients with ARDS.American journal of physiology. Lung cellular and molecular physiology · 2026
    Article
  2. Article
  3. Article
  4. Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Alger M FredericksDepartment of Surgery, Rhode Island Hospital, Brown University, 593 Eddy Street, Middle House 211, Providence, RI, 02903, USA.
Li Juan WangDepartment of Pathology, Rhode Island Hospital, Brown University, 593 Eddy Street, Providence, RI, 02903, USA.
William G FairbrotherMCB Department, Brown University, 70 Ship Street, Room 4040, Providence, RI, 02903, USA.
Alfred AyalaDepartment of Surgery, Rhode Island Hospital, Brown University, 593 Eddy Street, Middle House 211, Providence, RI, 02903, USA.
Sean F MonaghanDepartment of Surgery, Rhode Island Hospital, Brown University, 593 Eddy Street, Middle House 211, Providence, RI, 02903, USA. smonaghan@lifespan.org.ORCID 0000-0003-1490-3043

Funding

Uncoupling of IL-1 beta and VEGF-A Crosstalk Contributes to Impaired Arteriogenesis Response to Ischemia in Chronic Diabetes MellitusP20GM103652 · NIGMS · OCEAN STATE RESEARCH INSTITUTE, INC. · PI HARRINGTON, ELIZABETH O · 2013 to 2022
$21.3M
Mechanisms of Immune Dysfunction and Morbid Outcome in Response to Shock/SepsisR35GM118097 · NIGMS · RHODE ISLAND HOSPITAL · PI AYALA, ALFRED · 2016 to 2025
$6.3M
Discovering Splicing Defects in Human GenesR01GM127472 · NIGMS · BROWN UNIVERSITY · PI William G Fairbrother · 2018 to 2026
$5.9M
American College of Surgeons C. James Carrico, MD, FACS, Faculty Research Fellowship for the Study of Trauma and Critical CareNIGMS NIH HHS L30 GM121094NIGMS NIH HHS P20 GM103652NIGMS NIH HHS P20GM103652NIGMS NIH HHS R01 GM127472NIGMS NIH HHS R01GM127472NIGMS NIH HHS R35 GM118097NIGMS NIH HHS R35GM118097
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Alternative SplicingRespiratory Distress SyndromeHumansPositive-Pressure Respiration

Identifiers

PMID32077999
PMCPMC7490973

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.