Evidence map›Paper›PMID 32077971›Full record

ReviewCellular and molecular life sciences : CMLS2020

Functional mosaic organization of neuroligins in neuronal circuits.

Liming Qin, Sile Guo, Ying Han, Xiankun Wang, Bo Zhang

Abstract readReview
In one paragraph

Review in Cellular and molecular life sciences : CMLS, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Atypical Cadherin FAT2 Is Required for Synaptic Integrity and Motor Behaviors.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2025
    Article
  3. Article
  4. Review
  5. Article
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Liming QinSchool of Chemical Biology and Biotechnology, Shenzhen Bay Laboratory, Peking University Shenzhen Graduate School, Shenzhen, 518055, China.ORCID http://orcid.org/0000-0003-1216-5278
Sile GuoSchool of Chemical Biology and Biotechnology, Shenzhen Bay Laboratory, Peking University Shenzhen Graduate School, Shenzhen, 518055, China.ORCID http://orcid.org/0000-0002-8070-2760
Ying HanSchool of Chemical Biology and Biotechnology, Shenzhen Bay Laboratory, Peking University Shenzhen Graduate School, Shenzhen, 518055, China.ORCID http://orcid.org/0000-0002-4336-7967
Xiankun WangSchool of Chemical Biology and Biotechnology, Shenzhen Bay Laboratory, Peking University Shenzhen Graduate School, Shenzhen, 518055, China.ORCID http://orcid.org/0000-0001-6347-1131
Bo ZhangSchool of Chemical Biology and Biotechnology, Shenzhen Bay Laboratory, Peking University Shenzhen Graduate School, Shenzhen, 518055, China. zbo@pku.edu.cn.ORCID http://orcid.org/0000-0003-2451-0593

Funding

Shenzhen-Hong Kong Institute of Brain Science 2019SHIBS0004
6 · The paper itself

Abstract

Complex brain circuitry with feedforward and feedback systems regulates neuronal activity, enabling neural networks to process and drive the entire spectrum of cognitive, behavioral, sensory, and motor functions. Simultaneous orchestration of distinct cells and interconnected neural circuits is underpinned by hundreds of synaptic adhesion molecules that span synaptic junctions. Dysfunction of a single molecule or molecular interaction at synapses can lead to disrupted circuit activity and brain disorders. Neuroligins, a family of cell adhesion molecules, were first identified as postsynaptic-binding partners of presynaptic neurexins and are essential for synapse specification and maturation. Here, we review recent advances in our understanding of how this family of adhesion molecules controls neuronal circuit assembly by acting in a synapse-specific manner.

Indexed as

AnimalsBrainCell Adhesion Molecules, NeuronalHumansNerve NetNeuronsSynapsesSynaptic TransmissionCell Adhesion Molecules, NeuronalNeurexinsNeuroliginsNeuronal circuitSynapse maturationSynapse specificationSynaptic adhesion molecules

Identifiers

PMID32077971
PMCPMC11104838

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.