Evidence map›Paper›PMID 32077852›Full record

ArticleeLife2020

Rapid regulation of vesicle priming explains synaptic facilitation despite heterogeneous vesicle:Ca

Janus Rl Kobbersmed, Andreas T Grasskamp, Meida Jusyte, Mathias A Böhme, Susanne Ditlevsen, Jakob Balslev Sørensen, Alexander M Walter

Open access · goldAbstract read
In one paragraph

Article in eLife, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
3.1field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 60 citations in OpenAlex.

  1. Article
  2. The Mechanism of LTXInternational journal of molecular sciences · 2025
    Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Frequency of Spontaneous Neurotransmission at Individual Boutons Corresponds to the Size of the Readily Releasable Pool of Vesicles.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2024
    Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Review
  13. Article
  14. Article
  15. A sequential two-step priming scheme reproduces diversity in synaptic strength and short-term plasticity.Proceedings of the National Academy of Sciences of the United States of America · 2022
    Article
  16. Article
  17. Review
  18. Three small vesicular pools in sequence govern synaptic response dynamics during action potential trains.Proceedings of the National Academy of Sciences of the United States of America · 2022
    Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 3 countries.

Janus Rl KobbersmedDepartment of Mathematical Sciences, University of Copenhagen, København, Denmark.ORCID 0000-0003-0313-6205
Andreas T GrasskampMolecular and Theoretical Neuroscience, Leibniz-Forschungsinstitut für Molekulare Pharmakologie, FMP im CharitéCrossOver, Berlin, Germany.ORCID 0000-0002-5895-6529
Meida JusyteMolecular and Theoretical Neuroscience, Leibniz-Forschungsinstitut für Molekulare Pharmakologie, FMP im CharitéCrossOver, Berlin, Germany.ORCID 0000-0001-9948-871X
Mathias A BöhmeMolecular and Theoretical Neuroscience, Leibniz-Forschungsinstitut für Molekulare Pharmakologie, FMP im CharitéCrossOver, Berlin, Germany.ORCID 0000-0002-0947-9172
Susanne DitlevsenDepartment of Mathematical Sciences, University of Copenhagen, København, Denmark.ORCID 0000-0002-1998-2783
Jakob Balslev SørensenDepartment of Neuroscience, University of Copenhagen, København, Denmark.ORCID 0000-0001-5465-3769
Alexander M WalterMolecular and Theoretical Neuroscience, Leibniz-Forschungsinstitut für Molekulare Pharmakologie, FMP im CharitéCrossOver, Berlin, Germany.ORCID 0000-0001-5646-4750
Leibniz-Forschungsinstitut für Molekulare Pharmakologie · DEUniversity of Copenhagen · DKUniversity of Nottingham · GB

Funding

Resource Component: Acquisition, maintenance and distribution of Drosophila stocksP40OD018537 · OD · TRUSTEES OF INDIANA UNIVERSITY · PI Annette L. Parks · 2014 to 2026
$13.5M
Deutsche Forschungsgemeinschaft 261020751Deutsche Forschungsgemeinschaft 278001972 - TRR 186Independent Research Fund Denmark 8141-00007BLundbeck Foundation R277-2018-802NIH HHS P40 OD018537
6 · The paper itself

Abstract

Chemical synaptic transmission relies on the Ca

Indexed as

AnimalsCalcium ChannelsDrosophilaSynaptic VesiclesCalcium Channelsca2+ channelsD. melanogastermathematical modellingneuroscienceshort-term plasticitystochastic simulationsynaptic transmissionvesicular release sites

Identifiers

PMID32077852
PMCPMC7145420
OpenAlexW3007037284

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.