Evidence map›Paper›PMID 32077689›Full record

ArticleBioconjugate chemistry2020

Tick Saliva Protein Evasin-3 Allows for Visualization of Inflammation in Arteries through Interactions with CXC-Type Chemokines Deposited on Activated Endothelium.

Stepan S Denisov, Alexandra C A Heinzmann, Tanja Vajen, Mark H M Vries, Remco T A Megens, Dennis Suylen, Rory R Koenen, Mark J Post, Johannes H Ippel, Tilman M Hackeng and 1 more

Open access · hybridAbstract read
In one paragraph

Article in Bioconjugate chemistry, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.6field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 9 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Review
  5. Review
  6. Article
  7. Immunomodulatory Proteins in Tick Saliva From a Structural Perspective.Frontiers in cellular and infection microbiology · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 1 institution in 2 countries.

Alexandra C A Heinzmann
Tanja Vajen
Mark H M Vries
Remco T A MegensInstitute for Cardiovascular Prevention, Ludwig-Maximilians-University, Pettenkoferstraße 8a, 80336, Munich, Germany.
Dennis Suylen
Mark J Post
Johannes H Ippel
Tilman M Hackeng
Ingrid Dijkgraaf
Maastricht University · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Atherosclerosis is one of the leading causes of mortality in developed and developing countries. The onset of atherosclerosis development is accompanied by overexpression of several inflammatory chemokines. Neutralization of these chemokines by chemokine-binding agents attenuates atherosclerosis progression. Here, we studied structural binding features of the tick protein Evasin-3 to chemokine (C-X-C motif) ligand

Indexed as

TicksAnimalsArthropod ProteinsCarotid Artery DiseasesChemokines, CXCEndothelium, VascularGlycosaminoglycansHumansHuman Umbilical Vein Endothelial CellsInflammationMiceArthropod ProteinsChemokines, CXCGlycosaminoglycans

Identifiers

PMID32077689
PMCPMC7086393
OpenAlexW3007834932

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.