Evidence map›Paper›PMID 32077361›Full record

Trial reportLeukemia & lymphoma2020

Randomized phase 1 study of sequential ("primed") vs. concurrent decitabine in combination with cladribine, cytarabine, G-CSF, and mitoxantrone (CLAG-M) in adults with newly diagnosed or relapsed/refractory acute myeloid leukemia (AML) or other high-grade myeloid neoplasm.

Raffaele Palmieri, Sarah A Buckley, Megan Othus, Anna B Halpern, Mary-Elizabeth M Percival, Bart L Scott, Paul C Hendrie, Pamela S Becker, Vivian G Oehler, Elihu H Estey and 1 more

Open access · greenAbstract readClinical Trial, Phase ILetterRandomized Controlled Trial
In one paragraph

Trial report in Leukemia & lymphoma, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.3field-weighted citation impact, top 45% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 9 citations in OpenAlex.

  1. Trial
  2. Article
  3. Article
  4. Article
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 1 country.

Raffaele PalmieriClinical Research Division, Fred Hutchinson Cancer Research Center/University of Washington, Seattle, WA, USA.
Sarah A BuckleyClinical Research Division, Fred Hutchinson Cancer Research Center/University of Washington, Seattle, WA, USA.
Megan OthusPublic Health Sciences Division, Fred Hutchinson Cancer Research Center, Seattle, WA, USA.
Anna B HalpernClinical Research Division, Fred Hutchinson Cancer Research Center/University of Washington, Seattle, WA, USA.
Mary-Elizabeth M PercivalClinical Research Division, Fred Hutchinson Cancer Research Center/University of Washington, Seattle, WA, USA.
Bart L ScottClinical Research Division, Fred Hutchinson Cancer Research Center/University of Washington, Seattle, WA, USA.
Paul C HendrieDepartment of Medicine, Division of Hematology, University of Washington, Seattle, WA, USA.
Pamela S BeckerClinical Research Division, Fred Hutchinson Cancer Research Center/University of Washington, Seattle, WA, USA.
Vivian G OehlerClinical Research Division, Fred Hutchinson Cancer Research Center/University of Washington, Seattle, WA, USA.
Elihu H EsteyClinical Research Division, Fred Hutchinson Cancer Research Center/University of Washington, Seattle, WA, USA.
Roland B WalterClinical Research Division, Fred Hutchinson Cancer Research Center/University of Washington, Seattle, WA, USA.
Fred Hutch Cancer Center · USUniversity of Washington · USSeattle Cancer Care Alliance · US

Funding

Translational Bioimaging Core Shared ResourceP30CA015704 · NCI · FRED HUTCHINSON CANCER RESEARCH CENTER · PI Eric Collisson · 1985 to 2026
$296.4M
RESEARCH TRAINING IN HEMATOLOGYT32HL007093 · NHLBI · UNIVERSITY OF WASHINGTON · PI Janis L Abkowitz · 1985 to 2026
$13.9M
NCI NIH HHS P30 CA015704NHLBI NIH HHS T32 HL007093
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

CladribineCytarabineDecitabineGranulocyte Colony-Stimulating FactorLeukemia, Myeloid, AcuteMitoxantroneAdultAntineoplastic Combined Chemotherapy ProtocolsHumansTreatment OutcomeCladribineCytarabineDecitabineGranulocyte Colony-Stimulating FactorMitoxantrone

Identifiers

PMID32077361
PMCPMC7384960
OpenAlexW3008185777

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.