ArticleHead and neck pathology2020
Demographic and Clinicopathologic Features of Actinic Cheilitis and Lip Squamous Cell Carcinoma: a Brazilian Multicentre Study.
Article in Head and neck pathology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 2 of them syntheses that pooled it.
What it found
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
16 citing papers in PubMed, 2 syntheses or guidelines pooled it, 35 citations in OpenAlex.
- Clinicopathological Analysis of Actinic Cheilitis: A Systematic Review with Meta-analyses.Head and neck pathology · 2023Pooled it
- Overview of oral health status and associated risk factors in maritime settings: An updated systematic review.PloS one · 2023Pooled it
- Remote Consultations for Monitoring Actinic Cheilitis: A Preliminary Non-Randomized Clinical Trial.Oral diseases · 2025Trial
- Multicenter study of oral and maxillofacial thrombi: analysis of 187 cases.Brazilian oral research · 2026Article
- Article
- Current and future burden trends of lip and oral cavity cancer based on estimated annual percentage change and the Bayesian age-period-cohort model: a study based on the global burden of disease 2021.Frontiers in oncology · 2025Article
- Squamous cell carcinoma and basal cell carcinoma of the lips: 25 years of experience in a northeast Brazilian population.Medicina oral, patologia oral y cirugia bucal · 2024Article
- Mast cells and factor XIIIa+ dendrocytes in actinic cheilitis and lip squamous cell carcinoma.Brazilian oral research · 2024Article
- Evaluation of lip diseases in peddlers on two beaches of Guarujá/Brazil: An observational study.Brazilian dental journal · 2024Observational
- Mucosal Leishmaniasis of the lip: Report of an Exuberant case in a Young man.Head and neck pathology · 2023Article
- Incidence and mortality rates of lip, oral cavity, and pharynx cancers in Brazil: time-trend and age-period-cohort analysis from the last 30 years, Global Burden of Disease Study.Revista da Sociedade Brasileira de Medicina Tropical · 2022Article
- Actinic Cheilitis - From Risk Factors to Therapy.Frontiers in medicine · 2022Review
- Actinic cheilitis in rural workers: prevalence and associated factors.Einstein (Sao Paulo, Brazil) · 2022Article
- Editorial: Recent advances in keratinocyte carcinomas: From molecular mechanisms to clinical perspectives.Frontiers in medicine · 2022Article
- Treatment Options and Post-Treatment Malignant Transformation Rate of Actinic Cheilitis: A Systematic Review.Cancers · 2021Review
- Influence of the patient's demographic profile and tumor characteristics on reconstructive techniques in lip cancers.Romanian journal of morphology and embryology = Revue roumaine de morphologie et embryologieArticle
Corrections and comments
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Authors and funding
24 authors at 10 institutions in 1 country.
Funding
Abstract
Data on the occurrence and clinicopathological characteristics of actinic cheilitis (AC) and lip squamous cell carcinoma (LSCC) are well studied; however, they are based on studies limited to a single centre. Herein, we described the frequency of AC and LSCC submitted to microscopic examination from representative geographic regions of Brazil. A retrospective multicentre study was performed on biopsies obtained from 1953 to 2018 at 10 Brazilian oral and maxillofacial pathology centres. A total of 198,709 biopsy specimens were surveyed. Sociodemographic data and clinicopathologic characteristics were analysed. A total of 2017 cases of ACs (1.0%) and 850 cases of LSCCs (0.4%) were recorded. A strong fair-skinned (> 87%) male (> 70%) predilection was observed in both conditions. The mean age was 54.8 ± 18.7 for individuals with AC and 57.8 ± 19.0 for individuals with LSCC. The most commonly affected site was the lower lip (> 90%). This is a large multicentre study of AC and LSCC from Brazil. The frequency and clinicopathological features of AC and LSCC were similar to those described worldwide. This study provides robust and representative epidemiological data of these conditions for the scientific community.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.