Evidence map›Paper›PMID 32076869›Full record

ArticleEuropean child & adolescent psychiatry2021

Risk factors for obsessive-compulsive symptoms. Follow-up of a community-based youth cohort.

Pedro Macul Ferreira de Barros, Maria Conceição do Rosário, Natalia Szejko, Natália Polga, Guaraci de Lima Requena, Beatriz Ravagnani, Daniel Fatori, Marcelo Camargo Batistuzzo, Marcelo Queiroz Hoexter, Luis Augusto Rohde and 4 more

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In one paragraph

Article in European child & adolescent psychiatry, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  8. Review
  9. A Study on Online Intervention for Early Childhood Eating Disorders during COVID-19.International journal of environmental research and public health · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Pedro Macul Ferreira de BarrosInstitute of Psychiatry, University of São Paulo, R. Dr. Ovídio Pires de Campos, 785, São Paulo, 05403-903, Brazil. pedro.macul@hc.fm.usp.br.ORCID http://orcid.org/0000-0002-1958-876X
Maria Conceição do RosárioChild and Adolescent Psychiatry Unit (UPIA), Department of Psychiatry, Federal University of São Paulo, São Paulo, Brazil.
Natalia SzejkoDepartment of Neurology, Medical University of Warsaw, Warsaw, Poland.
Natália PolgaGraduate Program in Psychology, Federal University of São Paulo, Santos, Brazil.
Guaraci de Lima RequenaDepartment of Statistics, Institute of Mathematics and Statistics, University of São Paulo, São Paulo, Brazil.
Beatriz RavagnaniInstitute of Psychiatry, University of São Paulo, R. Dr. Ovídio Pires de Campos, 785, São Paulo, 05403-903, Brazil.
Daniel FatoriInstitute of Psychiatry, University of São Paulo, R. Dr. Ovídio Pires de Campos, 785, São Paulo, 05403-903, Brazil.
Marcelo Camargo BatistuzzoInstitute of Psychiatry, University of São Paulo, R. Dr. Ovídio Pires de Campos, 785, São Paulo, 05403-903, Brazil.
Marcelo Queiroz HoexterInstitute of Psychiatry, University of São Paulo, R. Dr. Ovídio Pires de Campos, 785, São Paulo, 05403-903, Brazil.
Luis Augusto RohdeHospital de Clínicas de Porto Alegre, Federal University of Rio Grande Do Sul, Porto Alegre, Brazil.
Guilherme Vanoni PolanczykInstitute of Psychiatry, University of São Paulo, R. Dr. Ovídio Pires de Campos, 785, São Paulo, 05403-903, Brazil.
James Frederick LeckmanYale Child Study Center, Yale University School of Medicine, New Haven, USA.
Eurípedes Constantino MiguelInstitute of Psychiatry, University of São Paulo, R. Dr. Ovídio Pires de Campos, 785, São Paulo, 05403-903, Brazil.
Pedro Gomes de AlvarengaInstitute of Psychiatry, University of São Paulo, R. Dr. Ovídio Pires de Campos, 785, São Paulo, 05403-903, Brazil.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Environmental factors are at least as important as genetic factors for the development of obsessive-compulsive symptoms (OCS), but the identification of such factors remain a research priority. Our study aimed to investigate the association between a broad scope of potential risk factors and OCS in a large community cohort of children and adolescents. We evaluated 1877 participants and their caregivers at baseline and after 3 years to assess various demographic, prenatal, perinatal, childhood adversity, and psychopathological factors. Mean age at baseline was 10.2 years (SD 1.9) and mean age at follow-up was 13.4 years (SD 1.9). Reports of OCS at baseline and follow-up were analyzed using latent variable models. At preliminary regression analysis, 15 parameters were significantly associated with higher OCS scores at follow-up. At subsequent regression analysis, we found that eight of these parameters remained significantly associated with higher follow-up OCS scores while being controlled by each other and by baseline OCS scores. The significant predictors of follow-up OCS were: lower socioeconomic status (p = 0.033); lower intelligence quotient (p = 0.013); lower age (p < 0.001); higher maternal stress level during pregnancy (p = 0.028); absence of breastfeeding (p = 0.017); parental baseline OCS (p = 0.038); youth baseline anxiety disorder (p = 0.023); and youth baseline OCS scores (p < 0.001). These findings may better inform clinicians and policymakers engaged in the mental health assessment and prevention in children and adolescents.

Indexed as

ChildCohort StudiesCommunity NetworksComorbidityFemaleFollow-Up StudiesHumansMaleObsessive-Compulsive DisorderPsychopathologyRisk FactorsChildhood adverse eventsLongitudinal studyObsessive–compulsive symptomsPerinatal risk factorsPrenatal risk factors

Identifiers

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.