ArticleScience advances2020
Awake functional MRI detects neural circuit dysfunction in a mouse model of autism.
Article in Science advances, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 53 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
53 citing papers in PubMed, 2 syntheses or guidelines pooled it, 86 citations in OpenAlex.
- Where do we stand on fMRI in awake mice?Cerebral cortex (New York, N.Y. : 1991) · 2024Pooled it
- A systematic review of the relationship between magnetic resonance imaging based resting-state and structural networks in the rodent brain.Frontiers in neuroscience · 2023Pooled it
- SORDINO: silent, sensitive, specific and artifact-resistant fMRI in awake, behaving mice.Nature neuroscience · 2026Article
- Brain-Wide Activations Related to Forepaw Force Control Identified by Behaving Mouse FMRI.eNeuro · 2026Article
- Dup15q model mice exhibit impaired gastrointestinal motility and a constipation-like phenotype, alleviated by prucalopride.Translational psychiatry · 2026Article
- Restoration of axon initial segment plasticity via chemogenetic activation rescues autism-related behaviors.Cell death & disease · 2026Article
- RO4938581, a GABAMolecular psychiatry · 2026Article
- Article
- Longitudinal resting-state fMRI of awake mice during habituation: stress, head motion, and functional connectivity.Frontiers in neuroscience · 2026Article
- Biphasic acclimation for simultaneous wide-field fluorescent CaImaging neuroscience (Cambridge, Mass.) · 2026Article
- Stimulation at the frontal cortex influences the exercise activity and skeletal muscle status in senescence-accelerating mice.npj aging · 2025Article
- Longitudinal, simultaneous wide-field fluorescent Ca2+ imaging and fMRI in awake mice.bioRxiv : the preprint server for biology · 2025Article
- Magnetic resonance imaging cerebral blood perfusion measurement in awake mice.Journal of neuroscience methods · 2025Article
- High-dose medetomidine increases functional connectivity in the fear-related regions after electrical stimulation.Scientific reports · 2025Article
- Differential impacts of social isolation and enriched environment on multi-sensory brain-wide functionality and network segregation.Nature communications · 2025Article
- 3D transcranial ultrasound localization microscopy in awake mice: protocol and open-source pipeline.Communications engineering · 2025Article
- Age-dependent cortical overconnectivity in Shank3 mice is reversed by anesthesia.Translational psychiatry · 2025Article
- Awake rodent fMRI: Gradient-echo echo planar imaging versus compressed-sensing fast low-angle shot.Imaging neuroscience (Cambridge, Mass.) · 2025Article
- Genetically modified non-human primate models for research on neurodegenerative diseases.Zoological research · 2024Review
- Open-source versatile 3D-print animal conditioning platform design for in vivo preclinical brain imaging in awake mice and anesthetized mice and rats.Lab animal · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
11 authors at 5 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
MRI has potential as a translational approach from rodents to humans. However, given that mouse functional MRI (fMRI) uses anesthetics for suppression of motion, it has been difficult to directly compare the result of fMRI in "unconsciousness" disease model mice with that in "consciousness" patients. We develop awake fMRI to investigate brain function in
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.