Evidence map›Paper›PMID 32076616›Full record

ArticleBioMed research international2020

Platelet-Rich Plasma for Sport-Active Patients with Knee Osteoarthritis: Limited Return to Sport.

Sante Alessandro Altamura, Alessandro Di Martino, Luca Andriolo, Angelo Boffa, Stefano Zaffagnini, Annarita Cenacchi, Maria Stella Zagarella, Giuseppe Filardo

Open access · hybridAbstract read
In one paragraph

Article in BioMed research international, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 2 pooled it
7.6field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 2 syntheses or guidelines pooled it, 38 citations in OpenAlex.

  1. Platelet-rich plasma injections induce disease-modifying effects in the treatment of osteoarthritis in animal models.Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA · 2021
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  7. Combined subchondral and intra-articular injections of bone marrow aspirate concentrate provide stable results up to 24 months.Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Sante Alessandro AltamuraClinica Ortopedica e Traumatologica II IRCCS Istituto Ortopedico Rizzoli, Bologna, Italy.ORCID https://orcid.org/0000-0001-7066-4038
Alessandro Di MartinoClinica Ortopedica e Traumatologica II IRCCS Istituto Ortopedico Rizzoli, Bologna, Italy.ORCID https://orcid.org/0000-0002-2411-7508
Luca AndrioloClinica Ortopedica e Traumatologica II IRCCS Istituto Ortopedico Rizzoli, Bologna, Italy.ORCID https://orcid.org/0000-0001-6352-9671
Angelo BoffaClinica Ortopedica e Traumatologica II IRCCS Istituto Ortopedico Rizzoli, Bologna, Italy.
Stefano ZaffagniniClinica Ortopedica e Traumatologica II IRCCS Istituto Ortopedico Rizzoli, Bologna, Italy.
Annarita CenacchiServizio Trasfusionale Unico Metropolitano, Bologna, Italy.
Maria Stella ZagarellaServizio Trasfusionale Unico Metropolitano, Bologna, Italy.
Giuseppe FilardoApplied and Translational Research (ATR) Center IRCCS Istituto Ortopedico Rizzoli, Bologna, Italy.ORCID https://orcid.org/0000-0002-8136-0977
Istituto Ortopedico Rizzoli · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo evaluate a cohort of sport-active patients suffering from cartilage degeneration and OA, in terms of clinical outcome and return to sport (RTS) after platelet-rich plasma (PRP) injective treatment.

designThis study included forty-seven sport-active patients ≤50 years old with unilateral symptomatic knee cartilage degeneration or OA. Patients received 3 PRP injections and were prospectively evaluated at baseline and then at 2, 6, 12, and 24 months follow-up by IKDC subjective EQ-VAS, and Tegner scores. Furthermore, patients were asked about their RTS, in terms of return to any sport level or to their activity level before symptoms onset.

resultsIKDC subjective score improved significantly at all follow-ups, changing from 59.2 ± 13.6 to 70.6 ± 13 at 12 months and to 76.7 ± 12.5 at 24 months (

conclusionsSport-active patients affected by knee OA can benefit from PRP injections, with pain and function improvement over time. However, results are less satisfactory in terms of RTS since only half can achieve the same sport level as before the onset of symptoms. Patients undergoing PRP treatment should be made aware of their low chances to go back to high-impact sport activities.

Indexed as

Platelet-Rich PlasmaReturn to SportSportsAdrenal Cortex HormonesAdultFemaleHumansHyaluronic AcidKneeKnee JointMaleMiddle AgedOsteoarthritis, KneePainTreatment OutcomeAdrenal Cortex HormonesHyaluronic Acid

Identifiers

PMID32076616
PMCPMC7013341
OpenAlexW3003370942

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.