ReviewCureus2020
Chronic Non-cancer Pain Management and Addiction: A Review.
Review in Cureus, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
11 citing papers in PubMed, 24 citations in OpenAlex.
- Impact of the Osijek Multidisciplinary Biopsychosocial Program on Chronic Low Back Pain: A Prospective Randomized Controlled Study.International journal of environmental research and public health · 2026Trial
- Oxycodone/naloxone PR versus oxycodone PR in advanced cancer: A multi-centre randomised trial (ENhANCE trial).Palliative medicine · 2025Trial
- Medical cannabis authorization and opioid milligram equivalents over time in patients with chronic pain: a retrospective analysis.Pain medicine (Malden, Mass.) · 2026Article
- Correlates of mental defeat in individuals with chronic non-cancer pain on long-term opioid therapy.Pain medicine (Malden, Mass.) · 2025Article
- Factors Associated with Initiation of Opioid Use in a US Department of Veterans Affairs Pain Clinic: A Retrospective Study.Brain sciences · 2025Article
- Impact evaluation of an interdisciplinary approach to patients with chronic non-cancer pain in Chilean primary care.BMC health services research · 2025Article
- Adverse Events of the Long-Term Use of Opioids for Chronic Non-cancer Pain: A Narrative Review.Cureus · 2024Review
- The Association between Dysbiosis and Neurological Conditions Often Manifesting with Chronic Pain.Biomedicines · 2023Review
- Cannabis for Rheumatic Disease Pain: a Review of Current Literature.Current rheumatology reports · 2022Review
- A mobile health + health coaching application for the management of chronic non-cancer pain in older adults: Results from a pilot randomized controlled study.Frontiers in pain research (Lausanne, Switzerland) · 2022Article
- Cues conditioned to withdrawal and negative reinforcement: Neglected but key motivational elements driving opioid addiction.Science advances · 2021Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 2 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The use of opioids in chronic non-cancer pain (CNCP) has been a fast-rising treatment phenomenon in the last two decades. Though opioids are advocated in various chronic pain management guidelines, their use in chronic non-cancer pain still remains controversial as evidence of this approach is still weak. This paper highlights potential adverse effects associated with opioid use in pain management, including an increase in tolerance, dependence, and addiction outcomes. Nonetheless, opioids have an important place in contemporary CNCP management for selected patients. However, pain management must involve regular monitoring and the use of a multimodal pain management strategy. It is essential that the treating physician must be up-to-date with the form of therapy so that they have the requisite confidence to prescribe opioids and effectively manage adverse effects. Moreover, the adverse effects should be treated promptly to enhance patient compliance. Since this approach is beneficial for some patients, opioid treatment should only be applied on a case by case basis.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.