ArticleGlobal mental health (Cambridge, England)2020
Incidence of depression in people with newly diagnosed tuberculosis in Ethiopia: a cohort study.
Article in Global mental health (Cambridge, England), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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4 citing papers in PubMed, 10 citations in OpenAlex.
- Patients', caregivers' and healthcare workers' perspectives on integrating anxiety care in tuberculosis services in Pakistan: a qualitative interview study.BMC psychology · 2026Article
- Article
- Feedforward Control-Based Bundle Management for Hemoptysis in Pulmonary Tuberculosis Patients.Journal of multidisciplinary healthcare · 2025Article
- Problematic Alcohol Use in Debre Berhan, Ethiopia: A Community-Based Cross-Sectional Study.Substance use : research and treatmentArticle
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Authors and funding
4 authors at 2 institutions in 2 countries.
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No grant is acknowledged in the PubMed record.
Abstract
backgroundCross-sectional studies show that the prevalence of comorbid depression in people with tuberculosis (TB) is high. The hypothesis that TB may lead to depression has not been well studied. Our objectives were to determine the incidence and predictors of probable depression in a prospective cohort of people with TB in primary care settings in Ethiopia.
methodsWe assessed 648 people with newly diagnosed TB for probable depression using Patient Health Questionnaire, nine-item (PHQ-9) at the time of starting their anti-TB medication. We defined PHQ-9 scores 10 and above as probable depression. Participants without baseline probable depression were assessed at 2 and 6 months to measure incidence of depression. Incidence rates per 1000-person months were calculated. Predictors of incident depression were identified using Poisson regression.
resultsTwo hundred and ninety-nine (46.1%) of the participants did not have probable depression at baseline. Twenty-two (7.4%) and 26 (8.7%) developed depression at 2 and 6 months of follow up. The incidence rate of depression between baseline and 2 months was 73.6 (95% CI 42.8-104.3) and between baseline and 6 months was 24.2 (95% CI 14.9-33.5) per 1000 person-months respectively. Female sex (adjusted
conclusionThere was high incidence of probable depression in people undergoing treatment for newly diagnosed TB. The persistence and incidence of depression beyond 6 months need to be studied. TB treatment guidelines should have mental health component.
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