Evidence map›Paper›PMID 32076464›Full record

ArticleDisease markers2020

Association of Serum Uric Acid Concentration and Its Change with Cardiovascular Death and All-Cause Mortality.

Ze-Xuan Dong, Ming Tian, Hua Li, Yang Wu, Xing-Guo Du, Jun-Wu Dong, Hui-Hui Xiao, Li-Ping Dong, Xiao-Hong Song

Open access · hybridAbstract read
In one paragraph

Article in Disease markers, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
2.4field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it, 17 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Observational
  6. Article
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Ze-Xuan DongShanxi Medical University, Jinzhong, 030600 Shanxi, China.ORCID https://orcid.org/0000-0002-1101-530X
Ming TianDepartment of Nephrology, Wuhan Fourth Hospital, Puai Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430030 Hubei, China.ORCID https://orcid.org/0000-0002-0945-1516
Hua LiDepartment of Nephrology, Wuhan Fourth Hospital, Puai Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430030 Hubei, China.ORCID https://orcid.org/0000-0003-3885-942X
Yang WuDepartment of Nephrology, Wuhan Fourth Hospital, Puai Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430030 Hubei, China.ORCID https://orcid.org/0000-0003-4990-5217
Xing-Guo DuDepartment of Nephrology, Wuhan Fourth Hospital, Puai Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430030 Hubei, China.ORCID https://orcid.org/0000-0001-6757-3282
Jun-Wu DongDepartment of Nephrology, Wuhan Fourth Hospital, Puai Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430030 Hubei, China.ORCID https://orcid.org/0000-0002-3777-4160
Hui-Hui XiaoDepartment of Internal Medicine, JiangHan University, Wuhan, 430030 Hubei, China.ORCID https://orcid.org/0000-0001-5287-6782
Li-Ping DongDepartment of Nephrology, Wuhan Fourth Hospital, Puai Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430030 Hubei, China.ORCID https://orcid.org/0000-0003-1507-1488
Xiao-Hong SongDepartment of Nephrology, Wuhan Fourth Hospital, Puai Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430030 Hubei, China.ORCID https://orcid.org/0000-0002-0214-1953
Wuhan Puai Hospital · CNJianghan University · CNShanxi Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveThere is no consensus on the role of abnormal uric acid (UA) levels in the prognosis of patients undergoing hemodialysis. We therefore aimed to investigate the effects of changes in UA concentration on the risk of all-cause death and cardiac death in such patients.

methodIn this retrospective cohort study, patients admitted to two hemodialysis centers performing maintenance hemodialysis (MHD) in Wuhan First Hospital and Fourth Hospital Hemodialysis Center from January 1, 2007, to October 31, 2017, were included.

resultsIn all, 325 patients undergoing MHD aged 59.7 ± 14.7 years, including 195 men (60%), were enrolled, with a median follow-up of 37 months. Serum UA (

conclusionLow UA levels were closely related to all-cause mortality in patients undergoing MHD. Although UA levels had no significant effect on cardiac death, they had a good predictive value for long-term prognosis in patients on MHD.

Indexed as

AdultAgedAged, 80 and overCause of DeathFemaleHumansKaplan-Meier EstimateKidney Failure, ChronicMaleMiddle AgedPrognosisRenal DialysisRetrospective StudiesROC CurveSurvival AnalysisUric AcidUric Acid

Identifiers

PMID32076464
PMCPMC7008257
OpenAlexW3004310915

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.