Evidence map›Paper›PMID 32076364›Full record

ArticleMaterials science & engineering. C, Materials for biological applications2020

Subcutaneous priming of protein-functionalized chitosan scaffolds improves function following spinal cord injury.

Trevor R Ham, Dipak D Pukale, Mohammad Hamrangsekachaee, Nic D Leipzig

Abstract read
In one paragraph

Article in Materials science & engineering. C, Materials for biological applications, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Article
  6. Novel Strategies for Spinal Cord Regeneration.International journal of molecular sciences · 2022
    Review
  7. Article
  8. Review
  9. Chitosan as an Underrated Polymer in Modern Tissue Engineering.Nanomaterials (Basel, Switzerland) · 2021
    Review
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Trevor R HamDepartment of Biomedical Engineering, University of Akron, Akron, OH, 44325.
Dipak D PukaleDepartment of Chemical and Biomolecular Engineering, University of Akron, Akron, OH, 44325.
Mohammad HamrangsekachaeeDepartment of Biomedical Engineering, University of Akron, Akron, OH, 44325.
Nic D LeipzigDepartment of Biomedical Engineering, University of Akron, Akron, OH, 44325.

Funding

ResourceP40OD011062 · OD · UNIVERSITY OF MISSOURI-COLUMBIA · PI Elizabeth C Bryda · 2012 to 2026
$24.0M
Central Nervous System Tissue Organogenesis via Precise Growth Factor TetheringR21NS096571 · NINDS · UNIVERSITY OF AKRON · PI LEIPZIG, NIC D · 2016 to 2017
$418k
NIH HHS P40 OD011062NINDS NIH HHS R21 NS096571
6 · The paper itself

Abstract

Strategies using neural stem cells (NSCs) to aid regeneration following spinal cord injury (SCI) show much promise, but challenges remain regarding implementation and efficacy. In this work, we explored the use of an NSC-seeded scaffold consisting of covalently immobilized interferon-

Indexed as

AnimalsChitosanGaitHydrogelsNeural Stem CellsSpinal Cord InjuriesTissue EngineeringTissue ScaffoldsChitosanHydrogelsgait analysisintracellular σ peptideNeural stem cellsspinal cord injurytissue engineering

Identifiers

PMID32076364
PMCPMC7030193

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.