Evidence map›Paper›PMID 32076270›Full record

ArticleNature2020

Hydrogen peroxide sensor HPCA1 is an LRR receptor kinase in Arabidopsis.

Feihua Wu, Yuan Chi, Zhonghao Jiang, Yuanyuan Xu, Ling Xie, Feifei Huang, Di Wan, Jun Ni, Fang Yuan, Xiaomei Wu and 24 more

Abstract read
PubMed Publisher
In one paragraph

Article in Nature, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 243 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
243citing papers in PubMed, 2 pooled it
74.6field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

243 citing papers in PubMed, 2 syntheses or guidelines pooled it, 535 citations in OpenAlex.

  1. Pooled it
  2. Abiotic Stress in Crop Production.International journal of molecular sciences · 2023
    Pooled it
  3. Article
  4. Review
  5. Emerging roles of glutaredoxins in plant metabolism.Journal of experimental botany · 2026
    Review
  6. Article
  7. Article
  8. Article
  9. Biology · 2026
    Article
  10. Review
  11. Review
  12. Article
  13. Review
  14. Mechanisms and balanced regulation of plant immunity.Nature reviews. Molecular cell biology · 2026
    Review
  15. Article
  16. Review
  17. Review
  18. Review
  19. Review
  20. Review

183 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

34 authors at 7 institutions in 2 countries.

Feihua WuDepartment of Biology, Duke University, Durham, NC, USA.
Yuan Chi *Department of Biology, Duke University, Durham, NC, USA.
Zhonghao Jiang *Department of Biology, Duke University, Durham, NC, USA.
Yuanyuan Xu *College of Life and Environmental Sciences, Hangzhou Normal University, Hangzhou, China.
Ling Xie *Department of Biochemistry and Biophysics, University of North Carolina, Chapel Hill, NC, USA.
Feifei Huang *Department of Biology, Duke University, Durham, NC, USA.
Di WanCollege of Life and Environmental Sciences, Hangzhou Normal University, Hangzhou, China.
Jun NiCollege of Life and Environmental Sciences, Hangzhou Normal University, Hangzhou, China.
Fang YuanDepartment of Biology, Duke University, Durham, NC, USA.
Xiaomei WuCollege of Life and Environmental Sciences, Hangzhou Normal University, Hangzhou, China.
Yanyan ZhangCollege of Life and Environmental Sciences, Hangzhou Normal University, Hangzhou, China.
Li Wang *Department of Biochemistry and Biophysics, University of North Carolina, Chapel Hill, NC, USA.
Rui YeDepartment of Biology, Duke University, Durham, NC, USA.
Benjamin ByeonDepartment of Biology, Duke University, Durham, NC, USA.
Wenhua WangDepartment of Biology, Duke University, Durham, NC, USA.
Shu ZhangCollege of Life and Environmental Sciences, Hangzhou Normal University, Hangzhou, China.
Matthew SimaDepartment of Biology, Duke University, Durham, NC, USA.
Suping ChenCollege of Life and Environmental Sciences, Hangzhou Normal University, Hangzhou, China.
Minghua ZhuDepartment of Immunology, Duke University Medical Center, Durham, NC, USA.
Jessica PeiDepartment of Biology, Duke University, Durham, NC, USA.
Douglas M JohnsonDepartment of Physics, Duke University, Durham, NC, USA.
Shan ZhuDepartment of Biology, Duke University, Durham, NC, USA.
Xiaoqiang CaoCollege of Life and Environmental Sciences, Hangzhou Normal University, Hangzhou, China.
Christopher PeiDepartment of Biology, Duke University, Durham, NC, USA.
Zijing ZaiDepartment of Biology, Duke University, Durham, NC, USA.
Yihao LiuDepartment of Biology, Duke University, Durham, NC, USA.
Tianyi LiuDepartment of Biology, Duke University, Durham, NC, USA.
Gary B SwiftDepartment of Physics, Duke University, Durham, NC, USA.
Weiguo ZhangDepartment of Immunology, Duke University Medical Center, Durham, NC, USA.
Min YuDepartment of Horticulture, Foshan University, Foshan, China.
Zhangli HuCollege of Life Sciences and Oceanography, Shenzhen University, Shenzhen, China.
James N SiedowDepartment of Biology, Duke University, Durham, NC, USA.
Xian ChenDepartment of Biochemistry and Biophysics, University of North Carolina, Chapel Hill, NC, USA.
Zhen-Ming PeiDepartment of Biology, Duke University, Durham, NC, USA. zpei@duke.edu.
Duke University · USHangzhou Normal University · CNShenzhen University · CNUniversity of North Carolina at Chapel Hill · USDuke University Hospital · USFoshan University · CNEmory University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hydrogen peroxide (H

Indexed as

ArabidopsisArabidopsis ProteinsCalciumCalcium ChannelsCalcium SignalingCysteineEnzyme ActivationHydrogen PeroxideMembrane ProteinsMutationOxidation-ReductionPlant CellsProtein DomainsProtein Serine-Threonine KinasesArabidopsis ProteinsAt5g49760 protein, ArabidopsisCalciumCalcium ChannelsCysteineHydrogen PeroxideMembrane ProteinsProtein Serine-Threonine Kinases

Identifiers

PMID32076270
OpenAlexW3007711390

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.